2,6-di-tert-butyl-4-methyl-phenol; 4 Angstroem molecular sive; lithium chloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in N,N-dimethyl-formamide T=110°C; P=760 Torr; 44 h;

LiCl; CO; dichloro{1,1'-bis(diphenylphosphino)ferrocene}palladium(II) in N,N-dimethyl-formamide the triflate and the stannane in DMF contg. the Pd catalyst and LiCl heated at 110°C under 1 atm CO for 44 h; cooled to room temp., dild. with ether, filtered, filtrate washed with water and satd. NaCl soln., dried, concd., chromd. (flash column, hexanes/EtOAc);

1: 1,3-benzodioxol-5-yl-lt;tetrahydro-2H-1,4-oxazin-4-ylgt;-methanethione With sodium iodide; Merrifield resin in water; N,N-dimethyl-formamide T=100°C; Solid phase reaction; 24 h; 2: Bu2CuLi in tetrahydrofuran T=-78°C; Solid phase reaction; 5 h;

tin(IV) chloride in dichloromethane T=10 - 15°C; 0.25 h;

bromine; acetic acid T=20°C; 2 h;