potassium tert-butylate in tert-butyl alcohol T=90°C; 24 h;

indium in tetrahydrofuran T=20°C; 0.666667 h;

trimethylsilyl trifluoromethanesulfonate; [VO(OEt)Cl2] in dichloromethane 0 deg C, 2 h; RT, 6 h;

1: 1) TMEDA, n-BuLi / 1) in dry ether at reflux for 1h 2) -22 deg C overnight 2: 65 percent / potassium tert-butoxide / 2-methyl-propan-2-ol / 24 h / 90 °C View Scheme

magnesium in diethyl ether

暂无反应条件数据

1: 70 percent / pyridine, SOCl2 / benzene / 2.5 h / Heating 2: 1.) Mg turnings / 1.) ether, reflux, 30 min; 2.) ether, reflux, 2 h View Scheme

1: 80 percent / NaBH4, 5percent NaOH / methanol; H2O / 12 h 2: 70 percent / pyridine, SOCl2 / benzene / 2.5 h / Heating 3: 1.) Mg turnings / 1.) ether, reflux, 30 min; 2.) ether, reflux, 2 h View Scheme

1: 1) TMEDA, n-BuLi / 1) in dry ether at reflux for 1h 2) CO2 as a continous stream for 1h 2: 1) SOCl2 3: 1) BF3*THF 2) NaOH, H2O2 / 1) for 1h 2) at 50 deg C for 1h 4: 95 percent / triethylamine / CH2Cl2 / -22 °C 5: 94 percent / LiBr / dimethylformamide 6: 84 percent / Mg / tetrahydrofuran 7: 72 percent / 4.5M HCl / H2O / 18 h / Heating View Scheme