2-氧代-3-苯基丙酸甲酯合成路线 （共 25 条）
反应条件
1: 72 percent / DBU / dimethylformamide / 2.5 h 2: 77 percent / K2CO3 / dimethylformamide / 4 h / Ambient temperature View Scheme
参考文献
Namiki; Baba; Suzuki; Nishikawa; Sawada; Itoh; Oku; Kitaura; Hashimoto
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 4 p. 1404 - 1414
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide T=0°C; 2.5 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 35, # 6 p. 2594 - 2597
反应条件
(R)-N-dicyclohexylphosphino-N-methyl-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine; hydrogen; bis(cycloocta-1,5-diene)rhodium(I) trifluoromethanesulfonate in tetrahydrofuran T=25°C; P=15514.4 Torr; 6 h; Title compound not separated from byproducts;
参考文献
Boaz, Neil W.; Mackenzie, Elaine B.; Debenham, Sheryl D.; Large, Shannon E.; Ponasik Jr., James A.
Journal of Organic Chemistry, 2005 , vol. 70, # 5 p. 1872 - 1880
反应条件
(R)-N-dicyclohexylphosphino-N-methyl-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine; hydrogen; bis(cycloocta-1,5-diene)rhodium(I) trifluoromethanesulfonate in tetrahydrofuran T=25°C; P=15514.4 Torr; 6 h; Title compound not separated from byproducts;
参考文献
Boaz, Neil W.; Mackenzie, Elaine B.; Debenham, Sheryl D.; Large, Shannon E.; Ponasik Jr., James A.
Journal of Organic Chemistry, 2005 , vol. 70, # 5 p. 1872 - 1880
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide
T=0°C;
参考文献
Namiki; Baba; Suzuki; Nishikawa; Sawada; Itoh; Oku; Kitaura; Hashimoto
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 4 p. 1404 - 1414
反应条件
gold(III) chloride; silver hexafluoroantimonate in 1,4-dioxane
T=20°C; 0.166667 h; regioselective reaction;
参考文献
Gudla, Vanajakshi; Balamurugan, Rengarajan
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5243 - 5247
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide
T=0°C; 2.5 h;
参考文献
Brana, Miguel F; Garcia, M Luisa; Lopez, Berta; de Pascual-Teresa, Beatriz; Ramos, Ana; Pozuelo, Jose M; Dominguez, M Teresa
Organic and biomolecular chemistry, 2004 , vol. 2, # 13 p. 1864 - 1871
反应条件
hydrogenchloride in tetrahydrofuran
0.5 h; Ambient temperature;
参考文献
Shin; Yonezawa; Yamada
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 3934 - 3944
反应条件
hydrogenchloride in tetrahydrofuran
0.5 h; Ambient temperature;
参考文献
Shin; Yonezawa; Yamada
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 3934 - 3944
反应条件
hydrogenchloride in tetrahydrofuran
0.5 h; Ambient temperature;
参考文献
Shin; Yonezawa; Yamada
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 3934 - 3944
