2-甲氧基-5-硝基苯酚合成路线 （共 96 条）
反应条件
bromine; acetic acid
参考文献
Huleatt, Paul B.; Choo, Sze Shiong; Chua, Sheena; Chai, Christina L.L.
Tetrahedron Letters, 2008 , vol. 49, # 36 p. 5309 - 5311
反应条件
mercury(II) diacetate; sodium acetate; acetic acid
Behandeln des in wss. KOH geloesten Reaktionsprodukts mit wss. HBr und Erwaermen des Reaktionsprodukts in Eisessig mit Brom;
参考文献
Drake; Harris; Jaeger
Journal of the American Chemical Society, 1948 , vol. 70, p. 168,170
参考文献
Jones; Robinson
Journal of the Chemical Society, 1917 , vol. 111, p. 913
反应条件
1: 60 percent / K2CO3 / acetone / 10 h / Heating
2: 70 percent / CsF, N,N-diethylaniline / 2 h / 210 °C
View Scheme
参考文献
Chilin; Rodighiero; Guiotto
Synthesis, 1998 , # 3 p. 309 - 312
反应条件
potassium carbonate in acetone
10 h; Heating;
参考文献
Chilin; Rodighiero; Guiotto
Synthesis, 1998 , # 3 p. 309 - 312
反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / Inert atmosphere
1.2: 18 h / 70 °C
2.1: sodium hydroxide / dimethyl sulfoxide / 5 h / 100 °C
2.2: pH 1 / Cooling with ice
View Scheme
参考文献
NEUROGEN CORPORATION
Patent: WO2008/118935 A1, 2008 ;
