4-羟基-2-巯基-5-甲基嘧啶合成路线 （共 18 条）
反应条件
ethanol; sodium ethanolate; thiourea 15 h; RefluxInert atmosphere;
参考文献
Gu, Shuang-Xi; Yang, Shi-Qiong; He, Qiu-Qin; Ma, Xiao-Dong; Chen, Fen-Er; Dai, Hui-Fang; Clercq, Erik De; Balzarini, Jan; Pannecouque, Christophe
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 23 p. 7093 - 7099
参考文献
Coffen; Schaer; Bizzarro; Cheung
Journal of Organic Chemistry, 1984 , vol. 49, # 2 p. 296 - 300
反应条件
sodium ethanolate in ethanol 7 h; Heating;
参考文献
Archiv der Pharmazie, , vol. 317, # 5 p. 425 - 430
参考文献
American Chemical Journal, , vol. 43, p. 32
反应条件
potassium hydroxide in ethanol 2 h; Heating;
参考文献
Youssef, Mohamed M.; Youssef, Ayman M. S.
Phosphorus, Sulfur and Silicon and the Related Elements, 2003 , vol. 178, # 1 p. 67 - 81
反应条件
1: 90 percent / KOH / ethanol / 2 h / Heating 2: 60 percent / POCl3 / dioxane / 2 h / Heating 3: 30 percent / aq. NH3 / 2 h / Heating View Scheme
参考文献
Youssef, Mohamed M.; Youssef, Ayman M. S.
Phosphorus, Sulfur and Silicon and the Related Elements, 2003 , vol. 178, # 1 p. 67 - 81
反应条件
sodium hydroxide; methyloxirane in water T=20°C;
参考文献
Novakov; Orlinson; Navrotskii
Russian Journal of Organic Chemistry, 2005 , vol. 41, # 4 p. 607 - 609
反应条件
oxygen; ozone in acetic acid 0.166667 h; Ambient temperature;
参考文献
Matsui; Kamiya; Kawamura; Shibata; Muramatsu
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 9 p. 2939 - 2941
反应条件
hydrogen bromide; H2O T=110°C; 48 h; Title compound not separated from byproducts.;
参考文献
Wu, Gang; Dong, Shuan; Ida, Ramsey; Reen, Nitin
Journal of the American Chemical Society, 2002 , vol. 124, # 8 p. 1768 - 1777
反应条件
thymidine phosphorylase from Escherichia coli in phosphate buffer T=35°C; pH=7.0; 2 h; Title compound not separated from byproducts;
参考文献
Hatano, Akihiko; Harano, Aiko; Kirihara, Masayuki
Chemistry Letters, 2006 , vol. 35, # 2 p. 232 - 233
