反应条件
1: 4-chloro nicotinic acid With oxalyl dichloride in dichloromethane; N,N-dimethyl-formamide T=20°C; 3 h; 2: methanol in dichloromethane; N,N-dimethyl-formamide 0.5 h;
参考文献
Bristol-Myers Squibb Company; Vrudhula, Vivekananda M.; Pan, Senliang; Rajamani, Ramkumar; Macor, John E.; Bronson, Joanne J.; Dzierba, Carolyn Diane; Nara, Susheel Jethanand; Karatholuvhu, Maheswaran Sivasamban
Patent: US2013/237555 A1, 2013 ;
Location in patent: Paragraph 0159 ;