2-氨基-5-氯苯甲酸合成路线 (共 147 条)
反应条件
1: manganese peroxide; hydrochloric acid / 150 °C / im Druckrohr 2: fuming nitric acid / Reduzieren des Nitrierungsprodukts mit Zinn und Salzsaeure View Scheme
参考文献
Chemische Berichte, , vol. 6, p. 175
反应条件
1: potassium permanganate; tetrabutylammomium bromide 2: hydrogen; palladium on activated charcoal View Scheme
参考文献
Asian Journal of Chemistry, , vol. 25, # 2 p. 1039 - 1042
参考文献
Journal of the American Chemical Society, , vol. 69, p. 3142
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 33, p. 36
参考文献
Chemische Berichte, , vol. 55, p. 221
反应条件
1: chloroacetic acid; 2-amino-5-chloro-benzoic acid With sodium hydroxide in water Heating; 2: acetic anhydride With sodium acetate in water; N,N-dimethyl-formamide Heating;
参考文献
Nirogi, Ramakrishna V.S.; Deshpande, Amol D.; Kambhampati, Ramasastri; Badange, Rajesh Kumar; Kota, Laxman; Daulatabad, Anand V.; Shinde, Anil K.; Ahmad, Ishtiyaque; Kandikere, Vishwottam; Jayarajan, Pradeep; Dubey
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 346 - 349
反应条件
ammonia; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in water; N,N-dimethyl-formamide T=20°C;
参考文献
Mahajan; Mahalakshmi
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 5 p. 1299 - 1300
反应条件
1: With hydrogenchloride; sodium nitrite in water T=0°C; 2: With ammonium hydroxide; hydroxylamine; copper(II) sulfate in water T=0 - 70°C;
参考文献
Vonlanthen, David; Mishchenko, Artem; Elbing, Mark; Neuburger, Markus; Wandlowski, Thomas; Mayor, Marcel
Angewandte Chemie - International Edition, 2009 , vol. 48, # 47 p. 8886 - 8890
反应条件
Erhitzen der Reaktionsloesung mit ammoniakal. wss. Kupfer(I)-sulfit-Loesung;
参考文献
Huntress; Cliff; Atkinson
Journal of the American Chemical Society, 1933 , vol. 55, p. 4262,4270
参考文献
Huebner; Weiss
Chemische Berichte, 1873 , vol. 6, p. 175