3-(2-甲氧基苯基）丙酸合成路线 （共 42 条）
反应条件
sodium hydroxide; sodium; mercury
参考文献
Ghosh, Somnath; Datta, Indira; Chakraborty, Rupak; Das, Tapas Kumar; Sengupta, Judhajit; Sarkar, Dipak Chandra
Tetrahedron, 1989 , vol. 45, # 5 p. 1441 - 1446
反应条件
hydrogen; potassium hydroxide in water T=20°C; P=760.051 Torr; 3 h; Sealed tube;
参考文献
Lim, Minkyung; De Castro, Kathlia A.; Oh, Seungchan; Lee, Kangsuk; Chang, Young-Wook; Kim, Hokun; Rhee, Hakjune
Applied Organometallic Chemistry, 2011 , vol. 25, # 1 p. 1 - 8
反应条件
1: With trimethylsilyl cyanide; P[2,4,6-(OMe)3C6H2]3 in acetonitrile T=25°C; 5 h; 2: With hydrogenchloride in diethyl ether; water T=20°C; 3 h;
参考文献
Hayashi, Masahiko; Kawabata, Hirotoshi; Yoshimoto, Kazuya; Tanaka, Takanori
Phosphorus, Sulfur and Silicon and the Related Elements, 2007 , vol. 182, # 2 p. 433 - 445
反应条件
1: With potassium carbonate; Pd-Tedicyp catalyst in N,N-dimethyl-formamide T=110°C; Heck reaction; 20 h; 2: With sodium hydroxide; water in N,N-dimethyl-formamide T=50 - 80°C;
参考文献
Lemhadri, Mhamed; Doucet, Henri; Santelli, Maurice
Tetrahedron, 2004 , vol. 60, # 50 p. 11533 - 11540
反应条件
1: 93 percent / piperidine, pyridine / 4 h / 85 - 110 °C 2: 96 percent / H2 / 10percent Pd/C / aq. ethanol / 2660 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 20 p. 2891 - 2898
反应条件
1: With sodium hydroxide in ethanol 2: With hydrogenchloride in water
参考文献
Mimori, Seisuke; Okuma, Yasunobu; Kaneko, Masayuki; Kawada, Koichi; Nomura, Yasuyuki; Murakami, Yasuoki; Hamana, Hiroshi
Chemistry Letters, 2013 , vol. 42, # 9 p. 1051 - 1052
反应条件
1.1: n-BuLi; NaH / tetrahydrofuran; hexane / 0.33 h / 0 °C 1.2: tetrahydrofuran; hexane / 2 h 2.1: 72 percent / ceric ammonium nitrate / acetonitrile / 4 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 71, # 12 p. 4516 - 4520
反应条件
1: 80 percent / 8.5percent NaOH / 45 °C 2: 75 percent / diethyl ether / 0 °C 3: 72 percent / SnCl2, HI, HCl / acetic acid 4: SOCl2 / benzene / Heating 5: 88 percent / benzene; diethyl ether 6: 3 percent / benzene / 9.5 h / Irradiation View Scheme
参考文献
Tetrahedron, , vol. 45, # 5 p. 1441 - 1446
反应条件
1: SOCl2 / benzene / Heating 2: 88 percent / benzene; diethyl ether 3: 3 percent / benzene / 9.5 h / Irradiation View Scheme
参考文献
Tetrahedron, , vol. 45, # 5 p. 1441 - 1446
反应条件
1: 72 percent / SnCl2, HI, HCl / acetic acid 2: SOCl2 / benzene / Heating 3: 88 percent / benzene; diethyl ether 4: 3 percent / benzene / 9.5 h / Irradiation View Scheme
参考文献
Tetrahedron, , vol. 45, # 5 p. 1441 - 1446
