2-萘-1-基-丙二酸二乙酯合成路线 （共 10 条）
反应条件
copper(l) iodide; caesium carbonate; 2-hydroxybiphenyl in tetrahydrofuran
T=70°C; 30 h;
参考文献
Hennessy, Edward J.; Buchwald, Stephen L.
Organic Letters, 2002 , vol. 4, # 2 p. 269 - 272
反应条件
tri-tert-butyl phosphine; sodium hydride; bis(dibenzylideneacetone)-palladium(0) in tetrahydrofuran
T=70°C; 6 h;
参考文献
Beare, Neil A.; Hartwig, John F.
Journal of Organic Chemistry, 2002 , vol. 67, # 2 p. 541 - 555
反应条件
1: 1-naphthylacetic acid ethyl ester With lithium hexamethyldisilazane in tetrahydrofuran
T=-78°C; 1 h; Inert atmosphere;
2: [(Cyanocarbonyl)oxy]ethane in tetrahydrofuran
T=-78 - 20°C; Inert atmosphere;
参考文献
Rios-Lombardia, Nicolas; Busto, Eduardo; Garcia-Urdiales, Eduardo; Gotor-Fernandez, Vicente; Gotor, Vicente
Journal of Organic Chemistry, 2009 , vol. 74, # 6 p. 2571 - 2574
反应条件
hydrogenchloride; sodium ethanolate; sodium in diethyl ether; ethanol; pentane
参考文献
Synthelabo
Patent: US5192797 A1, 1993 ;
反应条件
sodium ethanolate
unter Entfernen des entstehenden Aethanols;
参考文献
Wallingford; Homeyer; Jones
Journal of the American Chemical Society, 1941 , vol. 63, p. 2056,2058
参考文献
Blicke; Feldkamp
Journal of the American Chemical Society, 1944 , vol. 66, p. 1087,1090
反应条件
1: aq. ethanol
2: H2SO4 / Heating
3: (i) NaOEt, (ii) (decarboxylation)
View Scheme
参考文献
van Zanten,B.; Nauta,W.
Recueil des Travaux Chimiques des Pays-Bas, 1960 , vol. 79, p. 1211 - 1222
反应条件
1: H2SO4 / Heating
2: (i) NaOEt, (ii) (decarboxylation)
View Scheme
参考文献
van Zanten,B.; Nauta,W.
Recueil des Travaux Chimiques des Pays-Bas, 1960 , vol. 79, p. 1211 - 1222
反应条件
Reaktion ueber mehrere Stufen;
参考文献
Cope; Field
Journal of Organic Chemistry, 1949 , vol. 14, p. 856,859
反应条件
(i) NaOEt, (ii) (decarboxylation); Multistep reaction;
参考文献
van Zanten,B.; Nauta,W.
Recueil des Travaux Chimiques des Pays-Bas, 1960 , vol. 79, p. 1211 - 1222
