1: CH2Cl2 / 24 h / 20 °C 2: LiAlH4 / tetrahydrofuran / 2 h / 20 °C 3: Et3N / CH2Cl2 / 0.33 h / 0 °C 4: SnCl4 / CH2Cl2 / 1 h / 0 °C 5: 77 percent / Raney Ni / ethanol / 2 h / Heating 6: POCl3; K2CO3 / acetonitrile / 0.67 h / 60 °C View Scheme

1: CH2Cl2 / 24 h / 20 °C 2: LiAlH4 / tetrahydrofuran / 2 h / 20 °C 3: Et3N / CH2Cl2 / 0.33 h / 0 °C 4: SnCl4 / CH2Cl2 / 1 h / 0 °C 5: 78 percent / Raney Ni / ethanol / 2 h / Heating 6: POCl3; K2CO3 / acetonitrile / 0.67 h / 60 °C 7: NaBH4 / methanol / 1 h / Heating View Scheme

copper diacetate; palladium diacetate; potassium carbonate in toluene 24 h; Inert atmosphereReflux;

1: toluene / 3 h / Heating 2: 4.68 g / NaBH4 / methanol / 2 h / 20 °C 3: 89 percent / Et3N / CH2Cl2 / 3 h / 0 - 20 °C 4: 57 percent / tBuLi / pentane; tetrahydrofuran / 0.5 h / -100 - 0 °C 5: 87 percent / TFA; anisole / 24 h / Heating View Scheme

暂无反应条件数据

2: Et3N / dioxane / Irradiation View Scheme

1: 83 percent / Et3N / tetrahydrofuran / 12 h / Ambient temperature 2: 89 percent / CuI, Et3N / PdCl2(PPh3)2 / 6 h / Ambient temperature 3: 95 percent / K2CO3 / methanol / 0.5 h / Ambient temperature 4: 61 percent / n-Bu3SnH, AIBN / benzene / 5 h / Heating View Scheme