2-(2-溴-4,5-二甲氧基苯基)乙胺盐酸盐合成路线 （共 23 条）
参考文献
Bradsher, Charles K.; Hunt, David A.
Journal of Organic Chemistry, 1981 , vol. 46, # 2 p. 327 - 330
反应条件
1: 2.) NaBH4 / 1.) 120 deg C, 2.5 h, 2.) CHCl3, EtOH, r.t., 8 h
2: 1.) H3BO3, 2.) NaBH4 / 1.) CH3OH, H2O, r.t.
3: 16.4 percent / KI / Ni(PPh3)2Cl2-Zn-PPh3 / dimethylformamide / 55 °C
View Scheme
参考文献
Kihara, Masaru; Itoh, Joji; Iguchi, Seiichiro; Imakura, Yasuhiro; Kobayashi, Shigeru
Journal of Chemical Research, Miniprint, 1988 , # 1 p. 157 - 177
反应条件
1: toluene / 3 h / Heating
2: 5.22 g / NaBH4 / methanol / 2 h / 20 °C
3: 97 percent / Et3N / CH2Cl2 / 3 h / 0 - 20 °C
4: 70 percent / tBuLi / pentane; tetrahydrofuran / 0.5 h / -100 - 0 °C
5: 84 percent / TFA; anisole / 24 h / Heating
View Scheme
参考文献
Moreau, Anne; Couture, Axel; Deniau, Eric; Grandclaudon, Pierre
European Journal of Organic Chemistry, 2005 , # 16 p. 3437 - 3442
