4-(4-硝基苯氧基)苯甲醚合成路线 （共 36 条）
反应条件
hydrogen bromide; acetic acid 16 h; Inert atmosphereSchlenk techniqueReflux;
参考文献
Bao, Xiaofeng; Jin, Yanyan; Liu, Xiaolu; Liao, Hong; Zhang, Luyong; Pang, Tao
RSC Advances, 2014 , vol. 4, # 13 p. 6761 - 6775
反应条件
hydrogen; palladium on activated carbon in ethyl acetate P=2585.81 Torr; 18 h;
参考文献
Bayer Pharmaceuticals Corp.
Patent: EP1042305 B1, 2005 ;
Location in patent: Page/Page column 27 ;
反应条件
methyl pyridin-2-ylmethyl ketone; caesium carbonate; copper(I) bromide in dimethyl sulfoxide
T=90°C; 18 h; Inert atmosphere; chemoselective reaction;
参考文献
Yang, Shuliang; Wu, Cunqi; Ruan, Mingbo; Yang, Yanqin; Zhao, Yongxia; Niu, Jiajia; Yang, Wei; Xu, Jingwei
Tetrahedron Letters, 2012 , vol. 53, # 33 p. 4288 - 4292
反应条件
TMS-NEt2; phosphazene base t-Bu-P4 in hexane; N,N-dimethyl-formamide
T=20°C; 2 h;
参考文献
BAYER CORPORATION
Patent: US2004/102636 A1, 2004 ;
US 20040102636 A1
反应条件
CuO; potassium hydroxide in N,N-dimethyl acetamide
T=27°C; Ullmann Condensation; 28 h; Inert atmosphereSealed tube;
参考文献
Babu, S. Ganesh; Karvembu
Tetrahedron Letters, 2013 , vol. 54, # 13 p. 1677 - 1680
反应条件
P(i-BuNCH2CH2)3N in toluene
T=180°C; 1 h; microwave irradiation;
参考文献
Raders, Steven M.; Verkade, John G.
Tetrahedron Letters, 2008 , vol. 49, # 21 p. 3507 - 3511
反应条件
tetrabutylammomium bromide; potassium carbonate in n-hexyl ether; dimethyl sulfoxide
T=130°C; Ullmann reaction; 12 h; Open air atmosphere;
参考文献
Islam, Manirul; Mondal, Sanchita; Mondal, Paramita; Roy, Anupam Singha; Hossain, Dildar; Mobarak, Manir
Transition Metal Chemistry, 2011 , vol. 36, # 1 p. 1 - 11
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=110°C; 12 h;
参考文献
Arundhathi; Damodara; Likhar, Pravin R.; Kantam, M. Lakshmi; Saravanan; Magdaleno, Travis; Kwon, Sun Hee
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 9 p. 1591 - 1600
反应条件
1: 4-fluoro-nitro-benzene With potassium carbonate in DMF (N,N-dimethyl-formamide)
T=125°C; 2 h;
2: 4-methoxy-phenol in DMF (N,N-dimethyl-formamide)
T=125°C; 4 h;
参考文献
BAYER PHARMACEUTICALS CORPORATION
Patent: WO2005/35507 A2, 2005 ;
Location in patent: Page/Page column 59-60 ;
WO 2005/035507 A2
反应条件
copper(l) iodide; potassium carbonate in N,N-dimethyl-formamide
T=20 - 110°C;
参考文献
Sreedhar; Arundhathi; Reddy, P. Linga; Kantam, M. Lakshmi
Journal of Organic Chemistry, 2009 , vol. 74, # 20 p. 7951 - 7954
