1-(3,4-亚甲二氧基苯基)乙醇合成路线 （共 17 条）
反应条件
BPCC in dichloromethane 3.5 h;
参考文献
Guziec, Frank S.; Luzzio, Frederick A.
Synthesis, 1980 , # 9 p. 691 - 694
反应条件
oxygen; caesium carbonate; (-)-sparteine in toluene; tert-butyl alcohol T=60°C; P=760.051 Torr; 15 h; Molecular sieve; optical yield given as percent ee;
参考文献
Ebner, David C.; Bagdanoff, Jeffrey T.; Ferreira, Eric M.; McFadden, Ryan M.; Caspi, Daniel D.; Trend, Raissa M.; Stoltz, Brian M.
Chemistry - A European Journal, 2009 , vol. 15, # 47 p. 12978 - 12992
反应条件
1: Jones reagent 2: OH- 3: acetic acid / 2-ethoxy-ethanol 4: 1.) OH-, 2.) H2, 3.) POCl3 / 2.) Pd/C 5: TiCl4 6: NaBH4 7: 2.) DDQ 8: POCl3 View Scheme
参考文献
Ishii, Hisashi; Ishikawa, Tsutomu; Chen, Ih-Sheng; Ichikawa, Yuh-Ichiro
Heterocycles, 1984 , vol. 21, # 2 p. 711
反应条件
1: Bu4NOAc; Pd(IiPr)(OAc)2*(H2O); O2 / toluene / 12 h / 60 °C 2: 45 mg / PPh3; RhCl(PPh3)3 / toluene; dioxane; propan-2-ol / 50 °C View Scheme
参考文献
Lebel, Helene; Paquet, Valrie
Journal of the American Chemical Society, 2004 , vol. 126, # 36 p. 11152 - 11153
反应条件
sodium tetrahydroborate in methanol; dichloromethane
T=0°C; 0.5 h;
参考文献
Verma, Praveen Kumar; Sharma, Upendra; Kumar, Neeraj; Bala, Manju; Kumar, Vishal; Singh, Bikram
Catalysis Letters, 2012 , vol. 142, # 7 p. 907 - 913
反应条件
1: methyl iodide With magnesium in diethyl ether
T=0 - 5°C;
2: piperonal in diethyl ether
参考文献
Koul, Surrinder; Koul, Jawahir Lal; Singh, Budh; Kapoor, Munish; Parshad, Rajinder; Manhas, Kuldeep S.; Taneja, Subhash C.; Qazi, Ghulam N.
Tetrahedron Asymmetry, 2005 , vol. 16, # 15 p. 2575 - 2591
反应条件
in diethyl ether
2 h; Ambient temperature;
参考文献
Marsden, Richard; MacLean, David B.
Canadian Journal of Chemistry, 1984 , vol. 62, p. 1392 - 1399
反应条件
in diethyl ether
T=10 - 23°C; Inert atmosphere;
参考文献
Ebner, David C.; Bagdanoff, Jeffrey T.; Ferreira, Eric M.; McFadden, Ryan M.; Caspi, Daniel D.; Trend, Raissa M.; Stoltz, Brian M.
Chemistry - A European Journal, 2009 , vol. 15, # 47 p. 12978 - 12992
反应条件
(1R,2R)-α,α,α',α'-tetraphenyl-1,2-cyclohexanedimethanol; TiF4 in CH3CN
1) THF, hexane, 0 deg C to RT, 20 min, 2) THF, hexane, 20 min, 3) THF, hexane, -10 deg C, 12 h then warm to RT; Yield givenMultistep reaction;
参考文献
Pagenkopf, Brian L.; Carreira, Erick M.
Tetrahedron Letters, 1998 , vol. 39, # 52 p. 9593 - 9596
参考文献
Schmidt; Kircher; Kunz; Wahl; Hendriok
Journal of Organic Chemistry, 1995 , vol. 60, # 12 p. 3890 - 3894
