L-天门冬氨酸二苄酯盐酸盐合成路线 (共 6 条)
反应条件
1: T=20 - 90°C; 2: With sodium carbonate in water pH=10; 3: With hydrogenchloride in diethyl ether
参考文献
Bioorganic and Medicinal Chemistry, , vol. 18, # 17 p. 6220 - 6229
反应条件
1: 98 percent / CuCO3*Cu(OH)2 / ethanol; H2O / 2 h / 70 °C 2: 90 percent / Et3N / H2O; tetrahydrofuran / 12 h / Ambient temperature 4: HCl View Scheme
参考文献
Journal of Organic Chemistry, , vol. 58, # 9 p. 2369 - 2376
反应条件
1: 95 percent / benzene / 3.5 h / Heating 2: 98 percent / CuCO3*Cu(OH)2 / ethanol; H2O / 2 h / 70 °C 3: 90 percent / Et3N / H2O; tetrahydrofuran / 12 h / Ambient temperature 5: HCl View Scheme
参考文献
Journal of Organic Chemistry, , vol. 58, # 9 p. 2369 - 2376
参考文献
Journal of Organic Chemistry, , vol. 58, # 9 p. 2369 - 2376
参考文献
Journal of Organic Chemistry, , vol. 58, # 9 p. 2369 - 2376
反应条件
hydrogen bromide; acetic acid
参考文献
Kovacs,J. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 1839 - 1844