2,5-二甲氧基-4-硝基苯胺合成路线 （共 12 条）
反应条件
1: With pyridine; trifluorormethanesulfonic acid; lithium perchlorate in acetonitrile T=25°C; Electrochemical reaction; 2: With piperidine in acetonitrile T=80°C; 12 h; Electrochemical reaction; Overall yield = 95 percent;
参考文献
Journal of the American Chemical Society, , vol. 135, # 13 p. 5000 - 5003
反应条件
Hydrogen carbonate in methanol Deacylation; 24 h; Heating;
参考文献
Jackson, Yvette A.; Lyon, Michael A.; Townsend, Norman; Bellabe, Kettyna; Soltanik, Fernando
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 2 p. 205 - 210
反应条件
ammonium hydroxide T=150°C;
反应条件
1: 89 percent / HNO3; H2O / acetic acid / 1.5 h / 20 °C 2: 79 percent / Lawesson's reagent / toluene / 12 h / 80 °C 3: 100 percent / HCO3(-) / methanol / 24 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 2 p. 205 - 210
反应条件
1: 79 percent / Lawesson's reagent / toluene / 12 h / 80 °C 2: 100 percent / HCO3(-) / methanol / 24 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 2 p. 205 - 210
反应条件
1: aqueous nitric acid <86 percent >; acetic acid 2: aqueous ammonia / 150 °C View Scheme
反应条件
1: glacial acetic acid; nitric acid / 5 °C 2: alcoholic hydrochloric acid View Scheme
参考文献
Journal of the Chemical Society, , vol. 127, p. 2003
反应条件
1.1: NaNO2; AcOH; H2SO4 / 0.5 h / 40 °C 1.2: CuCl; HCl / 0.33 h / 80 °C 2.1: FeCl3*6H2O; NH2NH2; H2O / methanol / 1 h / 65 °C View Scheme
参考文献
Takemura, Shunji; Hirayama, Aya; Tokunaga, Junko; Kawamura, Fumie; Inagaki, Kyoko; Hashimoto, Kimiko; Nakata, Masaya
Tetrahedron Letters, 1999 , vol. 40, # 42 p. 7501 - 7505
反应条件
1: With acetic acid; isopentyl nitrite T=20°C; Inert atmosphere; 2: With hydrogenchloride; copper(l) chloride in water T=0 - 80°C; Inert atmosphere;
参考文献
Watanabe, Kana; Iwata, Yusuke; Adachi, Satoshi; Nishikawa, Tomoyuki; Yoshida, Yuko; Kameda, Shunsuke; Ide, Mitsuaki; Saikawa, Yoko; Nakata, Masaya
Journal of Organic Chemistry, 2010 , vol. 75, # 16 p. 5573 - 5579
