2,3-二氢-5-羟基-1,4-萘醌合成路线 （共 11 条）
反应条件
1: 1.) lithium aluminium hydride; 2.) CSA / 1.) THF, ether; 2.) r.t, 30-40 min 2: 12 mg / 1.) butyl lithium, diisopropylamine; 2.) MoO5*HMPA / 1.) hexane, THF, -70 deg C, 20 min; 2:) THF, -25 deg C, 30 min 3: 3 mg / 5percent HCl / tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Fujimoto; Satoh
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 11 p. 4540 - 4544
反应条件
copper(l) chloride in acetonitrile
T=20°C; Inert atmosphere;
参考文献
Yamashita, Mitsuaki; Kaneko, Masafumi; Tokuda, Harukuni; Nishimura, Katsumi; Kumeda, Yuko; Iida, Akira
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 17 p. 6286 - 6291
反应条件
hydrogenchloride; water; tin(ll) chloride
1 h; Reflux;
参考文献
Couche, Emmanuel; Fkyerat, Abdellatif; Tabacchi, Raffaele
Helvetica Chimica Acta, 2009 , vol. 92, # 5 p. 903 - 917
参考文献
Barrios, Luis; Ruiz, V. Manuel; Tapia, Ricardo; Valderrama, Jaime; Vega, Juan C.
Chemistry Letters, 1980 , p. 187 - 190
反应条件
hydrogenchloride; tin(ll) chloride
参考文献
Thomson
Journal of the Chemical Society, 1950 , p. 1737,1738, 1741
Journal of the Chemical Society, 1951 , p. 1237
反应条件
aluminium trichloride; sodium chloride
参考文献
Thomson
Journal of the Chemical Society, 1950 , p. 1737,1738, 1741
Journal of the Chemical Society, 1951 , p. 1237
参考文献
Thomson
Journal of the Chemical Society, 1952 , p. 1822,1823
Journal of the Chemical Society, 1951 , p. 1239
反应条件
in tetrahydrofuran; toluene
T=-40°C; 12 h; Inert atmosphere; regioselective reaction;
参考文献
Yamashita, Mitsuaki; Kaneko, Masafumi; Tokuda, Harukuni; Nishimura, Katsumi; Kumeda, Yuko; Iida, Akira
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 17 p. 6286 - 6291
反应条件
in pyridine; methanol
1 h; Ambient temperature;
参考文献
Brockmann, Hans; Laatsch, Hartmut
Liebigs Annalen der Chemie, 1983 , # 3 p. 433 - 447
反应条件
1: 95 percent / 10percent Na-dithionite / diethyl ether
2: 62 percent / methanol; pyridine / 1 h / Ambient temperature
View Scheme
参考文献
Brockmann, Hans; Laatsch, Hartmut
Liebigs Annalen der Chemie, 1983 , # 3 p. 433 - 447
