2-{[(4-甲基苯基)磺酰基]氨基}苯甲酸合成路线 （共 32 条）
反应条件
(i) PCl5, (ii) AlCl3, (iii) H2SO4; Multistep reaction;
参考文献
Hall,J.H. et al.
Journal of the American Chemical Society, 1972 , vol. 94, p. 4952 - 4958
反应条件
1.1: PCl5 / Heating 1.2: AlCl3 / 0 - 20 °C 2.1: aq. HCl / 1 h / cooling View Scheme
参考文献
Miyachi, Nobuhide; Yanagawa, Yoshinobu; Iwasaki, Hiroshi; Ohara, Yoshio; Hiyama, Tamejiro
Tetrahedron Letters, 1993 , vol. 34, # 51 p. 8267 - 8270
反应条件
1: PCl5 / 1,2-dichloro-ethane 2: AlCl3 / 1,2-dichloro-ethane 3: H2SO4 4: 90 percent / PTS View Scheme
参考文献
Miyachi, Nobuhide; Yanagawa, Yoshinobu; Iwasaki, Hiroshi; Ohara, Yoshio; Hiyama, Tamejiro
Tetrahedron Letters, 1993 , vol. 34, # 51 p. 8267 - 8270
反应条件
1: phosphorus (V)-chloride; carbon disulfide / Erwaermen der Reaktionsloesung mit Thiophen und Aluminiumchlorid 2: concentrated sulfuric acid 3: aqueous sulfuric acid; sodium nitrite / ueber das Diazoniumsalz View Scheme
参考文献
Steinkopf; Guenther
Justus Liebigs Annalen der Chemie, 1936 , vol. 522, p. 28,31
反应条件
in water
T=20°C; 0.5 h;
参考文献
Kamal, Ahmed; Reddy, J. Surendranadha; Bharathi, E. Vijaya; Dastagiri
Tetrahedron Letters, 2008 , vol. 49, # 2 p. 348 - 353
反应条件
pyridine hydrochloride in pyridine
8 h; Heating;
参考文献
Coutts, Ian G. C.; Edwards, Mark; Richards, David J.
Synthesis, 1981 , # 6 p. 487 - 489
反应条件
ammonium hydroxide; iron in methanol
T=25°C; Reduction; condensation; 1 h; sonication;
参考文献
Chandrasekhar; Narsihmulu
Tetrahedron Letters, 2000 , vol. 41, # 41 p. 7969 - 7972
反应条件
1: triethylamine / dichloromethane / 12.2 h / 0 - 20 °C
2: lithium hydroxide hydrate / methanol; water / 4 h / 0 - 20 °C
View Scheme
参考文献
Thorat, Vijaykumar H.; Ingole, Tukaram S.; Vijayadas, Kuruppanthara N.; Nair, Roshna V.; Kale, Sangram S.; Ramesh, Veera V.E.; Davis, Hilda C.; Prabhakaran, Panchami; Gonnade, Rajesh G.; Gawade, Rupesh L.; Puranik, Vedavati G.; Rajamohanan, Pattuparambil R.; Sanjayan, Gangadhar J.
European Journal of Organic Chemistry, 2013 , # 17 p. 3529 - 3542
反应条件
1: triethylamine / dichloromethane / 12.2 h / 0 - 20 °C
2: lithium hydroxide hydrate / methanol; water / 4 h / 0 - 20 °C
View Scheme
参考文献
Thorat, Vijaykumar H.; Ingole, Tukaram S.; Vijayadas, Kuruppanthara N.; Nair, Roshna V.; Kale, Sangram S.; Ramesh, Veera V.E.; Davis, Hilda C.; Prabhakaran, Panchami; Gonnade, Rajesh G.; Gawade, Rupesh L.; Puranik, Vedavati G.; Rajamohanan, Pattuparambil R.; Sanjayan, Gangadhar J.
European Journal of Organic Chemistry, 2013 , # 17 p. 3529 - 3542
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Grant, Barbara; Clecak, N. J.; Oxsen, Michael
Journal of Organic Chemistry, 1980 , vol. 45, # 4 p. 702 - 705
