4-叔丁基-2-硝基苯胺合成路线 （共 16 条）
反应条件
potassium hydroxide in ethanol 0.25 h; Inert atmosphereReflux;
参考文献
Frantz, Derik K.; Linden, Anthony; Baldridge, Kim K.; Siegel, Jay S.
Journal of the American Chemical Society, 2012 , vol. 134, # 3 p. 1528 - 1535
反应条件
1: AlCl3 / 1,2-dichloro-ethane 2: (i) HNO3, H2SO4, (ii) KOH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 90, p. 2049 - 2056
反应条件
1: 72 percent / conc. H2SO4, conc. HNO3 / 1 h 2: H2 / Pd/C / ethanol 3: 2 h / 110 °C 4: fuming nitric acid / 0 - 5 °C 5: 9 M HCl / 0.5 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 25 p. 4906 - 4916
反应条件
1: H2 / Pd/C / ethanol 2: 2 h / 110 °C 3: fuming nitric acid / 0 - 5 °C 4: 9 M HCl / 0.5 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 25 p. 4906 - 4916
反应条件
(i) HNO3, H2SO4, (ii) KOH; Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 90, p. 2049 - 2056
反应条件
1: 2 h / 110 °C 2: fuming nitric acid / 0 - 5 °C 3: 9 M HCl / 0.5 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 25 p. 4906 - 4916
反应条件
1: acetic acid; concentrated sulfuric acid; sodium nitrite / Erwaermen des Reaktionsprodukts nach Zusatz von Aethanol auf 80grad 2: Raney nickel / Hydrogenation View Scheme
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 71, p. 321,338
参考文献
Gelzer
Chemische Berichte, 1888 , vol. 21, p. 2956
反应条件
triethylamine in anhydrous xylene
参考文献
US2004/102636 A1, ;
US 20040102636 A1
反应条件
hydrogenchloride; tin(ll) chloride
参考文献
Kuhler; Fryklund; Bergman; Weilitz; Lee; Larsson
Journal of Medicinal Chemistry, 1995 , vol. 38, # 25 p. 4906 - 4916
