反应条件
1: KOH, PEG 400 / 0.5 h / 150 - 200 °C
2: p-TSA / 12 h / Ambient temperature
3: 96 percent / H2, quinoline / 5percent Pd/BaSO4 / hexane / Ambient temperature
4: 84 percent / O3 / CH2Cl2 / -78 °C
5: 1.) NaNH2 / 1.) THF, RT, 1 h, 2.) THF, from -10 deg C to RT
6: 96 percent / LAH / tetrahydrofuran / 5 h / -10 - 20 °C
View Scheme
参考文献
Narasimhan, S.; Mohan, H.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 11 p. 950 - 953
