(4-甲氧基苯基)(吡啶-2-基)甲酮合成路线 (共 20 条)
反应条件
oxygen; sodium hydride in tetrahydrofuran T=0 - 20°C; 6 h;
参考文献
Wang, Xinbo; Wang, David Zhigang
Tetrahedron, 2011 , vol. 67, # 19 p. 3406 - 3411
反应条件
1: in tetrahydrofuran T=-78 - 20°C; 2: With ammonium chloride in tetrahydrofuran
参考文献
US2010/160280 A1, ;
Page/Page column 79 ;
反应条件
caesium carbonate; 1,3-bis(2,4,6-trimethylphenyl)imidazolinium chloride; palladium diacetate in 1,4-dioxane T=120°C; P=37503 Torr; 45 h;
参考文献
Tetrahedron, , vol. 63, # 3 p. 682 - 689
反应条件
ferrous chloride tetrahydrate; oxygen; acetic acid in dimethyl sulfoxide T=100°C; 24 h;
参考文献
De Houwer, Johan; Abbaspour Tehrani, Kourosch; Maes, Bert U. W.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 11 p. 2745 - 2748
反应条件
carbon; toluene-4-sulfonic acid T=90°C; Friedel-Crafts reaction; 2.5 h;
参考文献
Sarvari, Mona Hosseini; Sharghi, Hashem
Helvetica Chimica Acta, 2005 , vol. 88, # 8 p. 2282 - 2287
反应条件
1.1: Mg / iodine / tetrahydrofuran / 2 h / Heating 1.2: tetrahydrofuran / 2 h / 0 - 20 °C 2.1: pyridinium chlorochromate / CH2Cl2 / 0.33 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 2 p. 219 - 232
反应条件
1.1: Mg / iodine / tetrahydrofuran / 2 h / Heating 1.2: tetrahydrofuran / 2 h / 0 - 20 °C 2.1: pyridinium chlorochromate / CH2Cl2 / 0.33 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 2 p. 219 - 232
反应条件
palladium diacetate; caesium carbonate; triphenylphosphine in N,N-dimethyl-formamide T=160°C; 24 h; Inert atmosphere;
参考文献
Arkivoc, , vol. 2012, # 9 p. 229 - 241
反应条件
PCy3*HBF4; palladium diacetate; potassium carbonate; 2,2,2-trimethylacetic acid in dimethyl amine T=100°C; 72 h; Inert atmosphere;
参考文献
Abarca, Belen; Adam, Rosa; Ballesteros, Rafael; Chiassai, Leonardo; Gamon, Cristina
Arkivoc, 2012 , vol. 2012, # 9 p. 229 - 241
反应条件
pyridinium chlorochromate
参考文献
Journal of the American Chemical Society, , vol. 122, # 51 p. 12663 - 12674