3-(2-氧代丙基)-氯化吡啶合成路线 （共 13 条）
反应条件
in tetrahydrofuran; hexane T=0°C; Grignard reaction;
参考文献
Hay, Michael P.; Turcotte, Sandra; Flanagan, Jack U.; Bonnet, Muriel; Chan, Denise A.; Sutphin, Patrick D.; Nguyen, Phuong; Giaccia, Amato J.; Denny, William A.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 2 p. 787 - 797
反应条件
[Pd(η3-1-Ph-allyl)(μ-Cl)]2; 2-methoxy-6-(N-methyl-N-phenyl-amino)phenyl(dicyclohexyl)phosphine; caesium carbonate T=90°C; 23 h; Inert atmosphereSchlenk techniqueSealed tube;
参考文献
Li, Pengbin; Lue, Bo; Fu, Chunling; Ma, Shengming
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 7 p. 1255 - 1259
反应条件
water; hydrogen bromide
参考文献
Journal of the American Chemical Society, , vol. 72, p. 1988
反应条件
hydrogenchloride; iron(III) chloride; iron in water
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 6 p. 924 - 939
反应条件
1: ammonium acetate 2: iron, ferric chloride hexahydrate, hydrochloric acid / H2O View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 6 p. 924 - 939
反应条件
1: ethanolic sodium ethylate solution 2: hydrobromic acid; water View Scheme
参考文献
Journal of the American Chemical Society, , vol. 72, p. 1988
反应条件
1: concentrated aqueous NH3 2: POCl3; NaCl; 1,2-dichloroethane 3: ethanolic sodium ethylate solution 4: hydrobromic acid; water View Scheme
参考文献
Journal of the American Chemical Society, , vol. 72, p. 1988
反应条件
1: POCl3; NaCl; 1,2-dichloroethane 2: ethanolic sodium ethylate solution 3: hydrobromic acid; water View Scheme
参考文献
Journal of the American Chemical Society, , vol. 72, p. 1988
参考文献
Journal of the American Chemical Society, , vol. 72, p. 1988
反应条件
KNH2 in acetone T=-38°C; chemical or electrochemical reductive stimulation of the reaction of various nucleophiles, at various catalysts; MechanismRate constant;
参考文献
Journal of the American Chemical Society, , vol. 107, p. 3451 - 3459
