1: With sulfuric acid in dichloromethane; water T=35°C; 0.166667 h; 2: With 1,3-dibromo-5,5-dimethyl-hydantoin in dichloromethane; water T=35°C; 24 h; 3: With sodium hydroxide in dichloromethane; water T=0 - 35°C; 0.333333 h;

1: 4-methyl-1H-imidazole With potassium carbonate in N,N-dimethyl-formamide T=100°C; 1 h; 2: 1-bromo-3-nitro-5-(trifluoromethyl)benzene in N,N-dimethyl-formamide T=108°C; 3.16667 h; Product distribution / selectivity;