4,7-二氯-3-喹啉羧酸合成路线 （共 1 条）
反应条件
1: With lithium hydroxide dihydrate; water in acetonitrile
T=20°C; 6 h; Cooling with ice;
2: With hydrogenchloride in water
pH=~ 8 - 9;
参考文献
AMGEN INC.; FISHER, Benjamin; JOHNSON, Michael G.; LUCAS, Brian; SHIN, Youngsook; KAIZERMAN, Amy
Patent: WO2012/61696 A1, 2012 ;
Location in patent: Page/Page column 58 ;
WO 2012/061696 A1
