N,N-二甲基-Β-丙氨酸合成路线 （共 21 条）
反应条件
1: With lithium hydroxide in ethanol; water T=20°C; 16 h; 2: in water pH=~ 6;
参考文献
EP929544 B1, ;
Page 27 ;
反应条件
hydrogenchloride in isopropyl alcohol
反应条件
1: With hydrogenchloride; Trizma Base; threo-1,4-dimercapto-2,3-butanediol; N-methyltransferase in water T=30°C; pH=8.0; 0.5 h; 2: With trichloroacetic acid in water Kinetics;
参考文献
WO2004/13092 A2, ;
Page 32; 35-36; 42-43 ;
反应条件
in toluene T=5°C; Industry scaleAutoclave;
参考文献
US2011/89020 A1, ;
Page/Page column 9 ;
反应条件
chromium(VI) oxide; sulfuric acid; trifluoroacetic acid in acetic acid
参考文献
Journal of the American Chemical Society, , vol. 94, p. 3877 - 3883
反应条件
1: (i) SOCl2, (ii) /BRN= 969212/, AlCl3 2: CF3CO2H, H2SO4, CrO3 / aq. acetic acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 94, p. 3877 - 3883
反应条件
T=20 - 35°C; 1.05 h; Sealed reactor; Product distribution / selectivity;
参考文献
Idemitsu Kosan Co., Ltd.
Patent: EP2426103 A1, 2012 ;
Location in patent: Page/Page column 16; 18 ;
参考文献
Journal of the American Chemical Society, , vol. 73, p. 3168,3171
US2526556 , ;
参考文献
Journal of the American Chemical Society, , vol. 55, p. 4576
反应条件
hydrogenchloride in diethyl ether
参考文献
Journal of Organic Chemistry, , vol. 31, p. 3948 - 3951
