2-氨基-3,4-二氢-1(2H)-萘酮盐酸盐(1:1)合成路线 （共 4 条）
反应条件
hydrogenchloride; water
T=100°C; 5 h;
参考文献
MITSUBISHI PHARMA CORPORATION; SANOFI-AVENTIS
Patent: WO2007/119463 A1, 2007 ;
Location in patent: Page/Page column 181; 182 ;
WO 2007/119463 A1
反应条件
hydrogenchloride; hydrogen; Pd-BaSO4 in methanol; water
P=2585.7 Torr; 1.33333 h;
参考文献
Hall, J. Herbert; Chien, Joseph Yuming; Kauffman, Joel M.; Litak, Peter T.; Adams, Jeffrey K.; et al.
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 5 p. 1245 - 1273
反应条件
potassium ethanolate in benzene
24 h; Ambient temperature;
参考文献
Delgado; Garcia; Mauleon; Minguillon; Subirats; Feliz; Lopez; Velasco
Canadian Journal of Chemistry, 1988 , vol. 66, # 3 p. 517-527
反应条件
1: 1.) t-BuOK, 2.) n-BuNO2, 3.) 12 M HCl
2: 50 percent / H2, 12 M HCl / Pd/BaSO4 / methanol; H2O / 1.33 h / 2585.7 Torr
View Scheme
参考文献
Hall, J. Herbert; Chien, Joseph Yuming; Kauffman, Joel M.; Litak, Peter T.; Adams, Jeffrey K.; et al.
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 5 p. 1245 - 1273
