N-Boc-L-叔亮氨酸合成路线 (共 25 条)
反应条件
triethylamine in methanol T=0 - 5°C;
参考文献
Vernalis (Oxford) Limited
Patent: US6716878 B1, 2004 ;
Location in patent: Page column 62 ;
反应条件
triethylamine in 1,4-dioxane; water
参考文献
Tibotec Pharmaceuticals Ltd.; MEDIVIR AB
Patent: EP1881002 A1, 2008 ;
反应条件
hydrogenchloride; sodium hydroxide in 1,4-dioxane; water; ethyl acetate
反应条件
in tetrahydrofuran; sodium hydroxide
参考文献
US5338726 A1, ;
US 5338726 A
反应条件
potassium hydroxide; potassium permanganate in water; tert-butyl alcohol
参考文献
Organic letters, , vol. 3, # 6 p. 897 - 899
反应条件
1: Et3N; DMAP / CH2Cl2 / 2 h / 20 °C 2: KMnO4; KOH / 2-methyl-propan-2-ol; H2O View Scheme
参考文献
Organic letters, , vol. 3, # 6 p. 897 - 899
反应条件
triethylamine in 1,4-dioxane; water 4 h; Ambient temperature;
参考文献
Tetrahedron, , vol. 47, # 29 p. 5453 - 5462
反应条件
sodium hydroxide in 1,4-dioxane
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 42, p. 1069 - 1076
反应条件
1: hydrogenchloride / methanol 2: triethylamine 3: lithium hydroxide hydrate / water View Scheme
参考文献
Journal of Organic Chemistry, , vol. 78, # 22 p. 11229 - 11237
反应条件
lithium hydroxide hydrate in water
参考文献
Journal of Organic Chemistry, , vol. 78, # 22 p. 11229 - 11237