bromine in chloroform 18 h; Ambient temperature;

sodium hydroxide; bromine in chloroform

bromine in dichloromethane T=25°C; 1 h;

1: 97 percent / triethylamine; copper(I) iodide / PdCl2(PPh3)2 / 3 h / 20 °C 2: 95 percent / Br2 / CH2Cl2 / 1 h / 25 °C View Scheme

bromine in dichloromethane T=25°C;

1: Diazotization.Reaktion ueber mehrere Stufen 2: bromine water View Scheme

1: palladium diacetate; triphenylphosphine; N,N,N',N,-tetramethylethylenediamine; sodium tetrahydroborate / tetrahydrofuran / 4 h / 20 °C / |Inert atmosphere 2: N,N,N',N,-tetramethylethylenediamine; sodium tetrahydroborate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / tetrahydrofuran / 2 h / 20 °C / |Inert atmosphere View Scheme

n-butyllithium; diethyl ether anschliessend Behandeln mit festem Kohlendioxid;

n-butyllithium Yield given. Multistep reaction;

sodium tetrahydroborate; N,N,N',N,-tetramethylethylenediamine; palladium diacetate; triphenylphosphine in tetrahydrofuran T=20°C; 4 h; Inert atmosphere; Reagent/catalystTime; regioselective reaction;