3-(苯基氨基)-2-丁烯酸乙酯合成路线 （共 36 条）
反应条件
1: diphenylether / 0.5 h / |Reflux 2: trichlorophosphate / 3 h / |Reflux View Scheme
参考文献
Luo, Wei; Liu, Yang; Wang, Jian; Guo, Chun; Lu, Wei-Qiang; Cui, Kun-Qiang
Medicinal Chemistry Research, 2012 , vol. 21, # 10 p. 3073 - 3079,7
参考文献
Hauser; Reynolds
Journal of the American Chemical Society, 1948 , vol. 70, p. 2402
反应条件
in N-methyl-acetamide; dichloromethane; water; ethyl acetate; trichlorophosphate
参考文献
American Cyanamid Company
Patent: US4925944 A1, 1990 ;
反应条件
1: diphenyl ether / Beim Erhitzen auf Siedetemperatur 2: sulfuric acid; nitric acid / 0 °C 3: phosphoryl chloride View Scheme
参考文献
Adams; Hey
Journal of the Chemical Society, 1949 , p. 3185,3187
反应条件
PPh3 gold(I) chloro complex; silver trifluoromethanesulfonate; potassium carbonate in dichloromethane
T=60°C; 5 h; SolventReagent/catalyst;
参考文献
Abdukader, Ablimit; Xue, Qicai; Lin, Aijun; Zhang, Ming; Cheng, Yixiang; Zhu, Chengjian
Tetrahedron Letters, 2013 , vol. 54, # 44 p. 5898 - 5900
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=80°C; 8 h;
参考文献
Hu, Hua-You; Liu, Yun; Ye, Miao; Xu, Jian-Hua
Synlett, 2006 , # 12 p. 1913 - 1917
反应条件
in toluene
15 h; Reflux;
参考文献
Sheibani, Hassan; Islami, Mohammad Reza; Nassab, Fatemeh Hosseini; Hassanpour, Avid
Arkivoc, 2006 , vol. 2006, # 15 p. 175 - 180
反应条件
2: alcoholic KOH-solution
View Scheme
参考文献
Lachowicz
Monatshefte fuer Chemie, 1896 , vol. 17, p. 357
反应条件
potassium acetate in ethanol
T=25°C; 6 h;
参考文献
Alberola, A.; Calvo, L. A.; Ortega, A. Gonzalez; Sadaba, M. L.; Sanudo, M. C.
Anales de Quimica, 1995 , vol. 91, # 3-4 p. 284 - 289
反应条件
methyl iodide
T=130 - 140°C;
参考文献
Knorr
Chemische Berichte, 1887 , vol. 20, p. 1397
Justus Liebigs Annalen der Chemie, 1886 , vol. 236, p. 73
