1: With sodium ethanolate in di-isopropyl ether
T=60°C;
2: With sulfuric acid in water
Heating / reflux;
3: With hydrazine in ethanol
T=0°C; Heating / reflux;
参考文献
TAKEDA CHEMICAL INDUSTRIES, LTD.
Patent: WO2003/99793 A1, 2003 ;
Location in patent: Page 271 ;