3-氧代-3-(3-吡啶基)丙酸乙酯合成路线 （共 29 条）
反应条件
1: palladium/BaSO4; acetic acid; HClO4 2: ethanolic KOH View Scheme
参考文献
Graef et al.
Journal of Organic Chemistry, 1946 , vol. 11, p. 257,263
反应条件
1: potassium ethylate; ethanol 2: aqueous HCl View Scheme
参考文献
Sugasawa et al.
Pharmaceutical Bulletin, 1954 , vol. 2, p. 39
反应条件
1: aqueous NaOH; NaNO2 2: ethanol; SnCl2+2 H2O; concentrated aqueous HCl View Scheme
参考文献
Burrus; Powell
Journal of the American Chemical Society, 1945 , vol. 67, p. 1468,1469
反应条件
1: aqueous NaOH; NaNO2 2: ethanol; SnCl2+2 H2O; concentrated aqueous HCl 3: palladium; aqueous HCl / Hydrogenation 4: platinum; aqueous HCl / Hydrogenation View Scheme
参考文献
Burrus; Powell
Journal of the American Chemical Society, 1945 , vol. 67, p. 1468,1469
反应条件
1: potassium ethylate; ethanol 2: aqueous HCl 3: ethanolic HCl View Scheme
参考文献
Sugasawa et al.
Pharmaceutical Bulletin, 1954 , vol. 2, p. 39
反应条件
1: 10percent aqueous ammonia / 1.) CH2Cl2, 0 deg C, 2.5 h, r.t., 2.) thermolysis 2: 93 percent / KOH / ethanol / 16 h / 80 °C 3: 86 percent / Cu / 160 - 220 °C / 12 Torr View Scheme
参考文献
Lions; Ritchie
Journal and Proceedings of the Royal Society of New South Wales, 1940 , vol. 74, p. 110,115
反应条件
(i) NH3, (ii) (hydrolysis), (decarboxylation); Multistep reaction;
参考文献
Ribereau,P. et al.
Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, 1975 , vol. 280, p. 293 - 296
反应条件
zinc(II) chloride in acetic acid T=100°C; 2 h;
参考文献
Pacheco,H.
Bulletin de la Societe Chimique de France, 1960 , p. 95 - 98
反应条件
1: palladium/BaSO4; acetic acid; HClO4
2: aqueous NH3
View Scheme
参考文献
Graef et al.
Journal of Organic Chemistry, 1946 , vol. 11, p. 257,263
参考文献
Balicki, Roman; Nantka-Namirski, Pawel
Polish Journal of Chemistry, 1982 , vol. 56, # 7/8/9 p. 963 - 973
