1: 40chlorobenzyl methanesulfonate With manganese in tetrahydrofuran T=20°C; Metallation; 0.5 h; 2: benzaldehyde in tetrahydrofuran; ethylene dibromide T=20°C; Addition; 0.5 h;

1: With pinacol borane; 1,4-di(diphenylphosphino)-butane; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate in tetrahydrofuran T=80°C; 72 h; 2: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran T=20°C; Further stages. Title compound not separated from byproducts.;

1: diethyl 4-chlorobenzyl phosphate With manganese in tetrahydrofuran T=20°C; 8 h; 2: benzaldehyde in tetrahydrofuran T=20°C; 1 h;

1: peroxybenzoic acid 2: LiAlH4; diethyl ether View Scheme

diethyl ether

lithium aluminium tetrahydride; diethyl ether

n-butyllithium 1.) THF, hexane, -78 gradC, 0.3 h; Yield given. Multistep reaction;

暂无反应条件数据