N-(3,4-二甲氧基苯乙基)乙酰胺合成路线 （共 31 条）
参考文献
Cui, Wenhua; Iwasa, Kinuko; Tokuda, Harukuni; Kashihara, Akiko; Mitani, Yosuke; Hasegawa, Tomoko; Nishiyama, Yumi; Moriyasu, Masataka; Nishino, Hoyoku; Hanaoka, Miyoji; Mukai, Chisato; Takeda, Kazuyoshi
Phytochemistry, 2006 , vol. 67, # 1 p. 70 - 79
反应条件
1: 60 percent / Et3N, DMAP / CH2Cl2 / Heating
2: 95 percent / n-BuLi / tetrahydrofuran; hexane / a) 0 deg C, 75 min, b) RT, overnight
View Scheme
参考文献
Lete, Esther; Collado, M. Isabel; Sotomayor, Nuria; Vicente, Teresa; Villa, Maria-Jesus
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 6 p. 1751 - 1758
反应条件
1: 70 percent / Et3N, DMAP / CH2Cl2 / Ambient temperature
2: 60 percent / Et3N, DMAP / CH2Cl2 / Heating
3: 95 percent / n-BuLi / tetrahydrofuran; hexane / a) 0 deg C, 75 min, b) RT, overnight
View Scheme
参考文献
Lete, Esther; Collado, M. Isabel; Sotomayor, Nuria; Vicente, Teresa; Villa, Maria-Jesus
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 6 p. 1751 - 1758
反应条件
1: 82 percent / AlCl3 / nitrobenzene / 2.5 h / 35 °C
2: 93 percent / 1N HCl / 18 h / Heating
3: NaBH4 / methanol / Ambient temperature
4: xylene / 24 h / Heating
5: 91 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating
View Scheme
参考文献
Orito, Kazuhiko; Matsuzaki, Tsutomu; Suginome, Hiroshi; Rodrigo, Russel
Heterocycles, 1988 , vol. 27, # 10 p. 2403 - 2412
反应条件
1: 87 percent / POCl3
2: 75 percent / phenethole / 10percent Pd/C / 1 h / Heating
3: 25 percent / SeO2
View Scheme
参考文献
Postaire, E.; Martinez, D.; Viel, C.; Chastagnier, M.; Hamon, M.
Bulletin de la Societe Chimique de France, 1988 , # 6 p. 982 - 988
反应条件
bromine in acetic acid
2 h; Ambient temperature;
参考文献
Kametani, Tetsuji; Ohsawa, Tatsushi; Ihara, Masataka
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 290 - 294
反应条件
1: polyphosphoric acid / dichloromethane / 2 h / 80 °C
2: methanol; sodium tetrahydroborate / 0.5 h / 20 °C
3: toluene-4-sulfonic acid / dichloromethane / 0.5 h / 20 °C
View Scheme
参考文献
Ivanov, Iliyan; Nikolova, Stoyanka; Aladjov, Dimo; Stefanova, Iliyana; Zagorchev, Plamen
Molecules, 2011 , vol. 16, # 8 p. 7019 - 7042
反应条件
1: 87 percent / POCl3
2: 75 percent / phenethole / 10percent Pd/C / 1 h / Heating
3: 25 percent / SeO2
4: 50 percent / NH2OH
5: 52 percent / Ac2O / Heating
View Scheme
参考文献
Postaire, E.; Martinez, D.; Viel, C.; Chastagnier, M.; Hamon, M.
Bulletin de la Societe Chimique de France, 1988 , # 6 p. 982 - 988
反应条件
Lawesson's reagent in toluene
2 h; Heating;
参考文献
Lete, Esther; Collado, M. Isabel; Sotomayor, Nuria; Vicente, Teresa; Villa, Maria-Jesus
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 6 p. 1751 - 1758
反应条件
trichlorophosphate in toluene
T=20 - 111°C; 2 h; Inert atmosphere;
参考文献
Soni, Rina; Cheung, Fung Kei; Clarkson, Guy C.; Martins, Jose E. D.; Graham, Mark A.; Wills, Martin
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 9 p. 3290 - 3294
