sodium hydroxide; acetic acid

1: 52 percent / toluene / 8 h / Heating 2: AcONH4 / 4 h / 135 °C 3: aq. HCl / 5 h / 90 °C 4: pyridine / 3 h / 20 °C View Scheme

1: 93 percent / methanol / 17 h / Heating 2: 88 percent / various solvent(s) / 0.17 h / 280 °C 3: 52 percent / toluene / 8 h / Heating 4: AcONH4 / 4 h / 135 °C 5: aq. HCl / 5 h / 90 °C 6: pyridine / 3 h / 20 °C View Scheme

1: AcONH4 / 4 h / 135 °C 2: aq. HCl / 5 h / 90 °C 3: pyridine / 3 h / 20 °C View Scheme

1: aq. HCl / 5 h / 90 °C 2: pyridine / 3 h / 20 °C View Scheme