反-1,3-二苯基-2-丙稀-1-醇合成路线 （共 76 条）
反应条件
4 A molecular sieve; magnesium; triethyl phosphite; bis(cyclopentadienyl)titanium dichloride in tetrahydrofuran T=0°C; 13 h;
参考文献
Ogata, Akitoshi; Nemoto, Masami; Kobayashi, Kenji; Tsubouchi, Akira; Takeda, Takeshi
Journal of Organic Chemistry, 2007 , vol. 72, # 10 p. 3816 - 3822
反应条件
1: Bromure de phenyl magnesium With lithium tetrachloromanganate(II) in tetrahydrofuran T=-10°C; 2: (2E)-1-(acetyloxy)-3-phenylprop-2-enyl acetate With chloro-trimethyl-silane; [Cu(CH3CN)4]BF4 in tetrahydrofuran T=0°C;
参考文献
Synthetic Communications, , vol. 35, # 23 p. 2967 - 2971
反应条件
tert.-butyl lithium in tetrahydrofuran; diethyl ether 1.) -78 deg C to -40 deg C over 1 h; -40 deg C, 1h, 2.) -78 deg C to 20 deg C, 2 h; 20 deg C, 14 h;
参考文献
Corey, E. J.; Kang, Jahyo
Journal of the American Chemical Society, 1982 , vol. 104, # 17 p. 4724 - 4725
反应条件
n-butyllithium in tetrahydrofuran T=-70°C;
参考文献
Satoh, Tsuyoshi; Kaneko, Youhei; Yamakawa, Koji
Tetrahedron Letters, 1986 , vol. 27, # 21 p. 2379 - 2382
反应条件
1: Methyltriphenylphosphonium bromide With phenyllithium; lithium bromide in tetrahydrofuran; anhydrous butyl ether T=-78 - 20°C; 0.166667 h; Inert atmosphere; 2: With phenyllithium in tetrahydrofuran; anhydrous butyl ether T=-78 - 20°C; 0.5 h; Inert atmosphere; 3: benzaldehyde regioselective reaction; Further stages;
参考文献
Hodgson, David M.; Persaud, Rosanne S. D.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 39 p. 7949 - 7951
反应条件
Pd(1,3-dimesityl-imidazole) carbene in tetrahydrofuran T=50°C; Tsuji-Trost reaction; 18 h;
参考文献
Journal of Organometallic Chemistry, , vol. 690, # 24-25 p. 5753 - 5758
反应条件
lithium aluminium tetrahydride; (2,6-t-Bu2-4-Me-C6H2O)2AlMe in diethyl ether; hexane; toluene T=-78°C; 0.25 h;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 61, p. 2241 - 2243
反应条件
chromium dichloride in N,N-dimethyl-formamide T=25°C; Substitution; 5 h;
参考文献
Journal of Organic Chemistry, , vol. 64, # 18 p. 6804 - 6814
反应条件
1: (E)-2-(2'-phenylethenyl)-1,3,2-benzodioxaborole With diethylzinc in hexane T=0°C; 0.0833333 h; 2: benzaldehyde in hexane; toluene T=0°C; 2 h; Further stages.;
参考文献
Chai, Zhuo; Liu, Xin-Yuan; Zhang, Jun-Kang; Zhao, Gang
Tetrahedron Asymmetry, 2007 , vol. 18, # 6 p. 724 - 728
反应条件
dichloromethyl silane; iron(III) chloride in ethylene glycol dimethyl ether T=84°C; 3 h;
参考文献
Organic Preparations and Procedures International, , vol. 39, # 4 p. 412 - 415
