2-氨基-2,4,6-环庚三烯-1-酮合成路线 （共 22 条）
反应条件
1: I2, aq. KI, K2CO3 / methanol 2: KOH / methanol View Scheme
参考文献
Nozoe,T. et al.
Bulletin of the Chemical Society of Japan, 1968 , vol. 41, p. 2978 - 2984
反应条件
potassium tert-butylate; 1,2-diphenyl-2-hydroxyethanone in benzene byproducts: benzil; under N2; t-BuOK added to stirred soln. of Ph3SbCl2 and H2NC7H5O (molar ratio 2:1:1) in dry benzene; stirred at room temp. for 30 min; benzoin (1 equiv.) added; heated under reflux for 1.5 h; solvent evapd.; sepd. by column chromy. (SiO2, CH2Cl2); further sepd. byTLC (SiO2, hexane-ethyl acetate);
参考文献
Bulletin of the Chemical Society of Japan, , vol. 76, # 5 p. 1029 - 1034
反应条件
potassium tert-butylate in dichloromethane byproducts: benzophenone; under N2; t-BuOK added to soln. of Ph3BiCl2 and H2NC7H5O (molar ratio 2:1:1) in CH2Cl2; stirred at room temp. for 5 min; benzopinacol (1 equiv.)added; stirred at room temp. for 1 h; solvent evapd.; sepd. by column chromy. (SiO2, CH2Cl2); further sepd. byTLC (SiO2, hexane-ethyl acetate);
参考文献
Bulletin of the Chemical Society of Japan, , vol. 76, # 5 p. 1029 - 1034
反应条件
potassium tert-butylate in dichloromethane T=0°C; 2 h;
参考文献
Mitsumoto, Yuhki; Nitta, Makoto
Heterocycles, 2001 , vol. 55, # 11 p. 2131 - 2137
反应条件
1: 11 percent / t-BuOK / CH2Cl2 / 2 h / 0 °C 2: 33 percent / aq. HCl / 6 h / 20 °C View Scheme
参考文献
Mitsumoto, Yuhki; Nitta, Makoto
Heterocycles, 2001 , vol. 55, # 11 p. 2131 - 2137
反应条件
hydrogenchloride in ethanol
T=50 - 80°C;
参考文献
Nozoe, Tetsuo; Takase, Kahei; Saito, Hiroaki; Yamamoto, Hiroshi; Imafuku, Kimiaki
Chemistry Letters, 1986 , p. 1577 - 1580
反应条件
hydrogenchloride in ethanol
T=50 - 80°C; 1 h;
参考文献
Nozoe, Tetsuo; Takase, Kahei; Yasunami, Masafumi; Ando, Masayoshi; Saito, Hiroaki; et al.
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 1 p. 128 - 142
参考文献
Doering; Knox
Journal of the American Chemical Society, 1951 , vol. 73, p. 828,838
Full Text Show Details
Nozoe et al.
Sci. Rep. Tohoku Univ., Ser. 1: Phys., Chem., Astron., 1952 , vol. # 36, p. 407,126,146
反应条件
1: 56 percent / Et3N
2: 19 percent / HCl / ethanol / 50 - 80 °C
View Scheme
参考文献
Nozoe, Tetsuo; Takase, Kahei; Saito, Hiroaki; Yamamoto, Hiroshi; Imafuku, Kimiaki
Chemistry Letters, 1986 , p. 1577 - 1580
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Hobson,J.D.; Malpass,J.R.
Journal of the Chemical Society [Section] C: Organic, 1967 , p. 1645 - 1648
