反应条件
1: 1.) aq. HCl, sodium nitrite, 2.) sodium acetate / 1.) from 0 deg C to 5 deg C, 2.) water, from 0 deg C to RT, 75 min 2: H2SO4 / 24 h / Heating 3: 84 percent / aq. LiOH / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Salituro, Francesco G.; Harrison, Boyd L.; Baron, Bruce M.; Nyce, Philip L.; Stewart, Kenneth T.; McDonald, Ian A.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 11 p. 2944 - 2946