反应条件
1: 3 g / NaBH4 / ethanol / Ambient temperature 2: 8.98 g / triethylamine, 4-pyrrolidinopyridine / CH2Cl2 / Ambient temperature 3: 30 percent / p-toluenesulfonic acid / benzene / 3.5 h / Heating 4: 1 M MeONa / 1.) methanol, -78 deg C, 10 min, 2.) -78 deg C, 2 h 5: 84 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h / Ambient temperature 6: 76 percent / MnO2 / ethyl acetate / Ambient temperature 7: 96 percent / n-BuLi / tetrahydrofuran; hexane / 1.) -78 deg C, 0.5 h, 2.) room temperature, 2 h 8: 50 percent / LiOH, water / 1,2-dimethoxy-ethane / 3 h / Ambient temperature View Scheme
参考文献
Young, Robert N.; Gauthier, Jacques Yves; Therien, Michel; Zamboni, Robert
Heterocycles, 1989 , vol. 28, # 2 p. 967 - 978
