7-硝基-3,4-二氢异喹啉合成路线 （共 10 条）
反应条件
1: manganese(IV) oxide / toluene / 2 h / Inert atmosphere; Reflux 2: palladium 10 on activated carbon; hydrogen / methanol / 3 h / 760.05 Torr 3: hydrogen bromide; copper(I) bromide; sodium nitrite / water / 12.5 h / 0 - 75 °C / Inert atmosphere View Scheme
参考文献
Shi, Jun; Manolikakes, Georg; Yeh, Chien-Hung; Guerrero, Carlos A.; Shenvi, Ryan A.; Shigehisa, Hiroki; Baran, Phil S.
Journal of the American Chemical Society, 2011 , vol. 133, # 20 p. 8014 - 8027
反应条件
1: palladium; decalin 2: ethanol; palladium/charcoal / Hydrogenation View Scheme
参考文献
Chen, Ying; Crockett, Richard D.; Wang, Xin; Larsen, Robert D.; Cui, Sheng; Faul, Margaret M.
Synlett, 2013 , vol. 24, # 3 art. no. ST-2012-Y0825-C, p. 301 - 304
反应条件
manganese(IV) oxide in toluene 2 h; Inert atmosphereReflux;
参考文献
Shi, Jun; Manolikakes, Georg; Yeh, Chien-Hung; Guerrero, Carlos A.; Shenvi, Ryan A.; Shigehisa, Hiroki; Baran, Phil S.
Journal of the American Chemical Society, 2011 , vol. 133, # 20 p. 8014 - 8027
反应条件
sulfuric acid; potassium nitrate
T=60°C; 4 h;
参考文献
Venkov, Atanas P.; Statkova-Abeghe, Stela
Synthetic Communications, 1996 , vol. 26, # 1 p. 127 - 134
反应条件
1: aq. NaOCl / CH2Cl2
2: NaOH / methanol; CH2Cl2
3: 72 percent / KNO3 / H2SO4 / 6 h / 20 - 60 °C
View Scheme
参考文献
Bohe, Luis; Kammoun, Majed
Tetrahedron Letters, 2004 , vol. 45, # 4 p. 747 - 751
反应条件
potassium nitrate in sulfuric acid
T=20 - 40°C; 2 h; Inert atmosphere;
参考文献
Chen, Ying; Crockett, Richard D.; Wang, Xin; Larsen, Robert D.; Cui, Sheng; Faul, Margaret M.
Synlett, 2013 , vol. 24, # 3 art. no. ST-2012-Y0825-C, p. 301 - 304
反应条件
1: NaOH / methanol; CH2Cl2
2: 72 percent / KNO3 / H2SO4 / 6 h / 20 - 60 °C
View Scheme
参考文献
Bohe, Luis; Kammoun, Majed
Tetrahedron Letters, 2004 , vol. 45, # 4 p. 747 - 751
反应条件
1: sodium hydroxide; N-bromosuccinmide / dichloromethane / |Inert atmosphere
2: potassium nitrate / sulfuric acid / 2 h / 20 - 40 °C / |Inert atmosphere
View Scheme
参考文献
Chen, Ying; Crockett, Richard D.; Wang, Xin; Larsen, Robert D.; Cui, Sheng; Faul, Margaret M.
Synlett, 2013 , vol. 24, # 3 art. no. ST-2012-Y0825-C, p. 301 - 304
反应条件
methanol; ammonia; benzene
参考文献
Schmitz
Chemische Berichte, 1958 , vol. 91, p. 1133,1138
反应条件
hydrogenchloride; tin(ll) chloride in ethanol
T=60°C; 1 h;
参考文献
Heer, Jag P.; Harling, John D.; Thompson, Mervyn
Synthetic Communications, 2002 , vol. 32, # 16 p. 2555 - 2563
