3,4,4-三甲氧基-四氢-2H-吡喃合成路线 （共 3 条）
反应条件
1: 4,4-dimethoxytetrahydro-2H-pyran-3-ol With sodium hydride in tetrahydrofuran
T=0°C; 1 h;
2: methyl iodide in tetrahydrofuran
T=20°C;
3: With ammonium chloride in tetrahydrofuran; water
参考文献
MERCK and CO., INC.; MERCK SHARP and DOHME LIMITED
Patent: WO2003/93266 A1, 2003 ;
Location in patent: Page/Page column 19 ;
WO 03/093266 A1
反应条件
1: 4,4-dimethoxytetrahydro-2H-pyran-3-ol With sodium hydride in tetrahydrofuran
T=0°C; 1 h;
2: methyl iodide in tetrahydrofuran
T=20°C;
参考文献
MERCK and CO., INC.
Patent: WO2005/14537 A2, 2005 ;
Location in patent: Page 48 ;
WO 2005/014537 A2
反应条件
hydrogenchloride in tetrahydrofuran; water
T=20°C; 1 h;
参考文献
MERCK and CO., INC.; MERCK SHARP and DOHME LIMITED
Patent: WO2003/93266 A1, 2003 ;
Location in patent: Page/Page column 20 ;
WO 03/093266 A1
