8-氨基-3,4-二氢萘-1(2H)-酮合成路线 （共 4 条）
反应条件
1: With hydrogenchloride in tetrahydrofuran; water T=40°C; 1 h; 2: With sodium hydrogencarbonate in tetrahydrofuran; water
参考文献
BAYER HEALTHCARE AG
Patent: WO2004/72020 A1, 2004 ;
Location in patent: Page 41-42 ;
WO 2004/072020 A1
反应条件
1: With hydrogenchloride in dichloromethane T=0°C; 0.75 h; 2: With sodium carbonate in water
参考文献
WO2010/127855 A1, ;
Page/Page column 150 ;
反应条件
1: With hydrogenchloride; water in 1,4-dioxane T=20°C; 2 h; 2: With lithium; tert-butyl alcohol in tetrahydrofuran; ammonia T=-78°C; Birch reduction; liquid NH3; 3: With hydrogenchloride; water in tetrahydrofuran T=40°C; 1 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 10 p. 3408 - 3411
反应条件
sodium tetrahydroborate in methanol T=0°C; 1 h;
参考文献
BAYER HEALTHCARE AG
Patent: WO2004/72020 A1, 2004 ;
Location in patent: Page 41-42 ;
WO 2004/072020 A1
