7-乙氧基萘-1-氨基甲酸叔丁酯合成路线 （共 3 条）
反应条件
1: With hydrogenchloride; water in 1,4-dioxane T=20°C; 2 h; 2: With lithium; tert-butyl alcohol in tetrahydrofuran; ammonia T=-78°C; Birch reduction; liquid NH3; 3: With hydrogenchloride; water in tetrahydrofuran T=40°C; 1 h;
参考文献
Urbahns, Klaus; Yura, Takeshi; Gupta, Jang B.; Tajimi, Masaomi; Fujishima, Hiroshi; Masuda, Tsutomu; Yamamoto, Noriyuki; Ikegami, Yuka; Marumo, Makiko; Yasoshima, Kayo; Yoshida, Nagahiro; Moriwaki, Toshiya; Madge, David; Chan, Fiona; Mogi, Muneto
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 10 p. 3408 - 3411
反应条件
caesium carbonate in acetonitrile
T=20°C;
参考文献
GRUeNENTHAL GMBH; FRANK, Robert; BAHRENBERG, Gregor; CHRISTOPH, Thomas; SCHIENE, Klaus; DE VRY, Jean; DAMANN, Nils; FRORMANN, Sven; LESCH, Bernhard; LEE, Jeewoo; KIM, Yong-Soo; KIM, Myeong-Seop
Patent: WO2010/127855 A1, 2010 ;
Location in patent: Page/Page column 148; 149 ;
反应条件
hydrogenchloride in 1,4-dioxane
T=0 - 20°C; 2 h;
参考文献
BAYER HEALTHCARE AG
Patent: WO2004/72020 A1, 2004 ;
Location in patent: Page 40-41 ;
WO 2004/072020 A1
