(1H-吲哚-3-基)-1-丙胺合成路线 （共 15 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C; Reflux; 2: With water; sodium hydroxide in tetrahydrofuran T=20°C;
参考文献
NOVARTIS AG
Patent: US2009/275560 A1, 2009 ;
Location in patent: Page/Page column 16 ;
反应条件
lithium aluminium tetrahydride in diethyl ether 3 h; Heating;
参考文献
Kuehne; Cowen; Xu; Borman
Journal of Organic Chemistry, 2001 , vol. 66, # 16 p. 5303 - 5316
反应条件
1.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 1.5 h / 20 °C 1.2: 96 percent / NH3(g) / tetrahydrofuran / 2.5 h / 20 °C 2.1: 86 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 15 p. 3823 - 3842
反应条件
hydrogen; nickel in methanol
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 2 p. 221 - 226
反应条件
1: 6M aq. K2CO3 / Ambient temperature 2: H2 / Raney-Ni / methanol View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 2 p. 221 - 226
参考文献
Journal of the American Chemical Society, , vol. 52, p. 5029,5031
反应条件
1: methanol. H2SO4 2: ethanol; aqueous N2H4 / 150 °C 3: NaNO2; aqueous acetic acid / Erwaermen des Reaktionsprodukts mit H2O 5: N2H4; aqueous ethanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 52, p. 5029,5031
反应条件
1: ethanol; aqueous N2H4 / 150 °C 2: NaNO2; aqueous acetic acid / Erwaermen des Reaktionsprodukts mit H2O 4: N2H4; aqueous ethanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 52, p. 5029,5031
反应条件
1: NaNO2; aqueous acetic acid / Erwaermen des Reaktionsprodukts mit H2O 3: N2H4; aqueous ethanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 52, p. 5029,5031
反应条件
2: N2H4; aqueous ethanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 52, p. 5029,5031
