反应条件
1: 0.46 g / CH2Cl2; H2O / 1 h / 0 °C 2: 82 percent / K2CO3; CuI; Cu / toluene / 48 h / Heating 3: 81 percent / BBr3 / CH2Cl2; 1,2-dichloro-ethane / 1 h / 20 °C 4: 70 percent / aq. NaOH / ethanol / 12 h / Heating View Scheme
参考文献
Kenny, Jane R.; Maggs, James L.; Meng, Xiaoli; Sinnott, Deborah; Clarke, Stephen E.; Park, B. Kevin; Stachulski, Andrew V.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 11 p. 2816 - 2825