1,4-二(溴甲基)苯合成路线 （共 136 条）
参考文献
Journal of the Chemical Society, , vol. 117, p. 525
反应条件
copper(I) bromide dimethylsulfide complex in diethyl ether T=0°C; 6 h;
参考文献
Tetrahedron Letters, , vol. 42, # 52 p. 9207 - 9210
反应条件
triethyl phosphite in ethanol; dichloromethane; toluene
参考文献
G. D. Searle and Co.
Patent: US4918064 A1, 1990 ;
参考文献
Nudelman, Ellen; Engel, Robert
Phosphorus, Sulfur and Silicon and the Related Elements, 1996 , vol. 111, p. 162
反应条件
sodium hydride 1.) tetrahydrofuran, 20 min, 2.) tetrahydrofuran, RT, 6 h; Multistep reaction;
参考文献
Bigge, Christopher F.; Johnson, Graham; Ortwine, Daniel F.; Drummond, James T.; Retz, Daniel M.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 8 p. 1371 - 1384
参考文献
Ladame, Sylvain; Faure, Regis; Denier, Colette; Lakhdar-Ghazal, Faouzi; Willson, Michele
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 11 p. 2070 - 2072
反应条件
1: lead nitrate; water 2: 140 °C / im Einschlussrohr View Scheme
参考文献
Wegscheider; Suida
Monatshefte fuer Chemie, 1912 , vol. 33, p. 1010
参考文献
Hayashi; Ueki; Harano; Komiya; Iyama
Chemical and pharmaceutical bulletin, 1964 , vol. 12, # 11 p. 1271 - 1276
反应条件
in N,N-dimethyl-formamide 3 h; Heating;
参考文献
Shrestha, Suja; Bhattarai, Bharat Raj; Kafle, Bhooshan; Lee, Keun-Hyeung; Cho, Hyeongjin
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 18 p. 8643 - 8652
参考文献
Zheng; Salgia; Thompson; Dillingham; Bond; Feng; Prasad; Gollamudi
Journal of Medicinal Chemistry, 1995 , vol. 38, # 1 p. 180 - 188
