potassium hydrogencarbonate in N,N-dimethyl-formamide T=25°C; 24 h;

1: 77 percent / Br2 / CCl4 / 1.5 h / 25 °C 2: 96 percent / BuLi / diethyl ether; hexane / -10 - 25 °C 3: 74 percent / KHCO3 / dimethylformamide / 24 h / 25 °C View Scheme

1: 96 percent / BuLi / diethyl ether; hexane / -10 - 25 °C 2: 74 percent / KHCO3 / dimethylformamide / 24 h / 25 °C View Scheme