三环[11.3.1.15,9]十八碳-1(17),5(18),6,8,13,15-己烯合成路线 （共 9 条）
反应条件
sodium in tetrahydrofuran; ammonia
Heating;
参考文献
Semmelhack,M.F.; Harrison,J.J.; Young,D.C.
Journal of the American Chemical Society, 1985 , vol. 107, p. 7508
反应条件
1: 1.) chromium hexacarbonyl; 2.) 2,2,6,6-tetramethylpiperidine, n-butyllithium, HMPA; 3.) iodine / 1.) p-dioxane, reflux, 60 h; 2.) THF/hexane, -78 deg C, 1 h, then 0 deg C, 1 h; 3.) THF/hexane, 25 deg C, 8 h
2: 91 percent / sodium / tetrahydrofuran; liquid ammonia / Heating
View Scheme
参考文献
Semmelhack,M.F.; Harrison,J.J.; Young,D.C.
Journal of the American Chemical Society, 1985 , vol. 107, p. 7508
反应条件
T=650°C; P=0.1 - 0.5 Torr;
参考文献
Otsubo,T. et al.
Bulletin of the Chemical Society of Japan, 1979 , vol. 52, # 5 p. 1515 - 1520
反应条件
1: 55 percent / NaOH, n-Bu4NI / H2O; CH2Cl2 / 8 h
2: 93 percent / H2NNH2*H2O, KOH / bis-(2-hydroxy-ethyl) ether / 6 h / 130 - 200 °C
View Scheme
参考文献
Sentou, Wakana; Satou, Teizi; Yasutake, Mikio; Lim, Chultack; Sakamoto, Youichi; Itoh, Tetsuji; Shinmyozu, Teruo
European Journal of Organic Chemistry, 1999 , # 5 p. 1223 - 1231
反应条件
1: 55 percent / NaOH, n-Bu4NI / H2O; CH2Cl2 / 8 h
2: 93 percent / H2NNH2*H2O, KOH / bis-(2-hydroxy-ethyl) ether / 6 h / 130 - 200 °C
View Scheme
参考文献
Sentou, Wakana; Satou, Teizi; Yasutake, Mikio; Lim, Chultack; Sakamoto, Youichi; Itoh, Tetsuji; Shinmyozu, Teruo
European Journal of Organic Chemistry, 1999 , # 5 p. 1223 - 1231
反应条件
lithium; tert-butyl alcohol
参考文献
Shinmyozu,T. et al.
Chemistry Letters, 1976 , p. 1405 - 1406
反应条件
1: Pb(OAc)4, LiCl, Py
2: Li, tBuOH
View Scheme
参考文献
Shinmyozu,T. et al.
Chemistry Letters, 1976 , p. 1405 - 1406
反应条件
Yield given. Multistep reaction;
参考文献
Krois, Daniel; Lehner, Harald
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 477 - 481
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Krois, Daniel; Lehner, Harald
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 477 - 481
