1,3,5-三甲氧基苯合成路线 （共 273 条）
反应条件
iron(III) chloride in carbon disulfide 4 h; Heating;
参考文献
Numata; Katsuno; Yamamoto; et al.
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 1 p. 325 - 331
反应条件
Et3NCH3 O3SOCH3; hexafluoroisopropyl alcohol T=50°C; Electrolysis;
参考文献
Kirste, Axel; Schnakenburg, Gregor; Stecker, Florian; Fischer, Andreas; Waldvogel, Siegfried R.
Angewandte Chemie - International Edition, 2010 , vol. 49, # 5 p. 971 - 975
反应条件
1: acetic acid / 110 °C / Air 2: PPh3 gold(I) chloro complex; acetic acid / 3 h / 110 °C View Scheme
参考文献
Pradal, Alexandre; Faudot Dit Bel, Pierre; Toullec, Patrick Y.; Michelet, Veronique
Synthesis (Germany), 2012 , vol. 44, # 15 p. 2463 - 2468
反应条件
1: 36.9 g / phosphoryl chloride / 1.5 h / Ambient temperature 2: 1.) m-chloroperbenzoic acid, 2.) aqueous potassium hydroxide / 1.) dichloromethane, room temperarure, 1.5 h, 2.) methanol, 0 deg C, 1 h 3: 59 percent / potassium carbonate, cooper(II) oxide / pyridine / 15 h / 140 °C 4: 90 percent / hydrogen chloride, titanium(IV) chloride / CH2Cl2 / 12 h / Ambient temperature 5: 620 mg / zinc, glacial acetic acid / 1 h 6: 518 mg / potassium carbonate / acetone / 23 h / Heating 7: 373 mg / potassium hydroxide / ethanol / 2 h / Heating 8: 247 mg / boron trichloride / CH2Cl2 / 1.) 0 deg C, 1 h, 2.) room temperature, 2 h View Scheme
参考文献
Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 403 - 411
反应条件
1: 98 percent / ZnCl2 2: 96 percent / 50 percent aq. KOH / ethanol / 6 h / 20 °C 3: 91 percent / AlCl3 / 10 h / 20 °C 4: 74 percent / I2; pyridine / 8 h / Heating View Scheme
参考文献
Lee, Yean-Jang; Wu, Tsao-Dong
Journal of the Chinese Chemical Society, 2001 , vol. 48, # 2 p. 201 - 206
反应条件
trifluorormethanesulfonic acid
参考文献
El-Khagawa, Ahmed M.
Bulletin de la Societe Chimique de France, 1987 , # 2 p. 372 - 374
反应条件
hydrogenchloride; aluminium trichloride; water 1.) Et2O, reflux, 1 h then r.t., overnight; Yield given. Multistep reaction;
参考文献
Bandgar, Babasaheb P.; Hote, Baliram S.; Nile, Shivraj H.
Letters in Drug Design and Discovery, 2011 , vol. 8, # 8 p. 725 - 732
反应条件
1: boron trifluoride diethyl etherate / ethyl acetate / 2 h / 20 °C 2: boron trichloride / dichloromethane / 2 h / 0 - 20 °C View Scheme
参考文献
Liu, Man; Zhang, Ji; Yang, Jian; Yang, Bo; Cui, Wei
Journal of Chemical Research, 2014 , vol. 38, # 3 p. 134 - 136
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; sodium hydride; N-methylaniline in diethyl ether; xylene T=95°C; 9 h;
参考文献
Loubinoux, B.; Coudert, G.; Guillaumet, G.
Synthesis, 1980 , # 8 p. 638 - 640
反应条件
boron trichloride in dichloromethane 20 h; Ambient temperature;
参考文献
Carvalho, Christopher F.; Russo, Albert V.; Sargent, Melvyn V.
Australian Journal of Chemistry, 1985 , vol. 38, # 5 p. 777 - 792
