ammonia; lithium in tetrahydrofuran; tert-butyl alcohol T=-78°C; 0.166667 h;

hydrogenchloride T=150°C; 48 h;

potassium hydroxide; potassium phosphate buffer; porcine kidney acylase I T=40°C; relative initial rate of hydrolysis, also with Aspergillus acylase I as a catalyst; with or without CoCl2;

potassium hydroxide; potassium phosphate buffer; porcine kidney acylase I T=40°C; relative initial rate of hydrolysis, also without CoCl2;

1: 93 percent / 2 M KOH / dioxane / 48 h / 25 °C 2: 88 percent / Li/liq. NH3 / tetrahydrofuran; 2-methyl-propan-2-ol / 0.17 h / -78 °C View Scheme

hydrogenchloride in water Heating;

1.1: sodium hydroxide / toluene / Heating 2.1: methanol / 6 h / 0 °C 3.1: hydrogen chloride / methanol / 0 - 20 °C 3.2: p-toluenesulfonic acid / xylene / 200 - 210 °C 4.1: potassium hydroxide / methanol / 2 h / Heating 5.1: lithium; liquid ammonia / ethanol; tetrahydrofuran / 0.08 h / -40 °C 6.1: hydrochloric acid / H2O / Heating View Scheme

1: potassium hydroxide / methanol / 2 h / Heating 2: lithium; liquid ammonia / ethanol; tetrahydrofuran / 0.08 h / -40 °C 3: hydrochloric acid / H2O / Heating View Scheme

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