双(4-二甲基氨基苯基 )乙炔合成路线 （共 12 条）
反应条件
α,α,α-trifluoro-o-cresol; CH3CH2CMo[N(t-Bu)(3,5-C6H3Me2)]3 in various solvent(s)
T=30°C; P=5 Torr; 22 h;
参考文献
Zhang, Wei; Kraft, Stefan; Moore, Jeffrey S.
Journal of the American Chemical Society, 2004 , vol. 126, # 1 p. 329 - 335
反应条件
potassium carbonate; i-Pr2NPPh2; palladium diacetate in tetrahydrofuran
T=65°C; 12 h;
参考文献
Zhang, Weiwei; Wu, Huayue; Liu, Zhiqing; Zhong, Ping; Zhang, Lin; Huang, Xiaobo; Cheng, Jiang
Chemical Communications, 2006 , # 46 p. 4826 - 4828
反应条件
NW(OC(CF3)2Me)3(DME) in toluene
T=95°C; 18 h; Inert atmosphere;
参考文献
Geyer, Andrea M.; Wiedner, Eric S.; Gary, J. Brannon; Gdula, Robyn L.; Kuhlmann, Nicola C.; Johnson, Marc J. A.; Dunietz, Barry D.; Kampf, Jeff W.
Journal of the American Chemical Society, 2008 , vol. 130, # 28 p. 8984 - 8999
反应条件
oxygen; cobalt(II)salen in methanol; chloroform
2 h; Ambient temperature;
参考文献
Inada, Akira; Nakamura, Yushin; Morita, Yutaka
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 3 p. 1041 - 1042
反应条件
1: diazomethyl-trimethyl-silane With n-butyllithium in diethyl ether; hexane
T=0°C; 1 h;
2: 4,4'-bis-(N,N-dimethylamino)-benzophenone in tetrahydrofuran; diethyl ether; hexane
T=0 - 20°C; 2 h;
参考文献
Finke, Aaron D.; Dumele, Oliver; Zalibera, Michal; Confortin, Daria; Cias, Pawel; Jayamurugan, Govindasamy; Gisselbrecht, Jean-Paul; Boudon, Corinne; Schweizer, W. Bernd; Gescheidt, Georg; Diederich, Francois
Journal of the American Chemical Society, 2012 , vol. 134, # 43 p. 18139 - 18146
反应条件
1: 71 percent / dichlorobis(triphenylphosphine)palladium(II); copper(I) chloride; triethylamine / 48 h / 80 °C
2: 87 percent / KOH / toluene / 5 h / Heating
3: 22 percent / dichlorobis(triphenylphosphine)palladium(II); copper(I) chloride; triethylamine / 24 h / 80 °C
View Scheme
参考文献
Umezawa, Hirohito; Okada, Shuji; Oikawa, Hidetoshi; Matsuda, Hiro; Nakanishi, Hachiro
Journal of Physical Organic Chemistry, 2005 , vol. 18, # 5 p. 468 - 472
反应条件
1: 1,2-bis(methylthio)acetylene With palladium diacetate; bis[2-(diphenylphosphino)phenyl] ether in tetrahydrofuran
0.166667 h; Inert atmosphere;
2: C8H10INZn*ClLi in tetrahydrofuran
T=25°C; 8 h; Inert atmosphere;
参考文献
Melzig, Laurin; Stemper, Jeremy; Knochel, Paul
Synthesis, 2010 , # 12 art. no. T04410SS, p. 2085 - 2091
反应条件
copper(l) iodide; triphenylphosphine; palladium dichloride in diethylamine
T=54 - 56°C;
参考文献
Rudenko, A. P.; Vasil'ev, A. V.
Russian Journal of Organic Chemistry, 1995 , vol. 31, # 10 p. 1360 - 1379
Zhurnal Organicheskoi Khimii, 1995 , vol. 31, # 10 p. 1502 - 1522
反应条件
n-butyllithium in tetrahydrofuran; hexane
T=-60 - 0°C; 0.5 h; Yield given;
参考文献
Mouries, Virginie; Waschbuesch, Rachel; Carran, John; Savignac, Philippe
Synthesis, 1998 , # 3 p. 271 - 274
反应条件
bis-triphenylphosphine-palladium(II) chloride; triethylamine; copper(l) chloride
T=80°C; Sonogashira reaction; 24 h;
参考文献
Umezawa, Hirohito; Okada, Shuji; Oikawa, Hidetoshi; Matsuda, Hiro; Nakanishi, Hachiro
Journal of Physical Organic Chemistry, 2005 , vol. 18, # 5 p. 468 - 472
