1-(1-氯乙基)-4-异丁基苯合成路线 （共 14 条）
反应条件
toluene-4-sulfonic acid; triphenylphosphine; lithium chloride; palladium on activated charcoal in water; butanone T=115°C; Carbonylation; P=40503.2 Torr; 4 h; Title compound not separated from byproducts;
参考文献
Jayasree; Seayad; Chaudhari
Chemical Communications, 1999 , # 12 p. 1067 - 1068
反应条件
hydrogenchloride; water; triphenylphosphine; 1 Rh/C in butanone T=115°C; P=41372.9 Torr;
参考文献
Council of Scientific and Industrial Research
Patent: US6660883 B1, 2003 ;
Location in patent: Page column 50-51 ;
反应条件
Al-anode in N,N-dimethyl-formamide T=20°C; electrocarboxylation;
参考文献
Damodar; Krishna Mohan; Khaja Lateef; Jayarama Reddy
Synthetic Communications, 2005 , vol. 35, # 9 p. 1143 - 1150
反应条件
toluene-4-sulfonic acid; triphenylphosphine; lithium chloride; palladium on activated charcoal in water; butanone T=115°C; Carbonylation; P=40503.2 Torr; 4 h; Title compound not separated from byproducts;
参考文献
Jayasree; Seayad; Chaudhari
Chemical Communications, 1999 , # 12 p. 1067 - 1068
反应条件
tetrabutylammomium bromide; dimethyl 1,3-benzenedicarboxylate in 1-methyl-pyrrolidin-2-one
T=25°C; Carboxylation; P=760 Torr; Electrolysis; Product distributionKinetics; Further Variations:Catalystssubstrate conc., catalyst conc., cathode material;
参考文献
Scialdone, Onofrio; Filardo, Giuseppe; Galia, Alessandro; Mantione, Davide; Silvestri, Giuseppe
Acta Chemica Scandinavica, 1999 , vol. 53, # 10 p. 800 - 806
反应条件
potassium hydroxide; tert-butyl-pyrocatechol; tetrabutylammomium bromide
T=120°C; 1 h;
参考文献
Neibecker, Denis; Reau, Regis; Lecolier, Serge
Journal of Organic Chemistry, 1989 , vol. 54, # 22 p. 5208 - 5210
反应条件
tetrabutylammomium bromide; dimethyl 1,3-benzenedicarboxylate in 1-methyl-pyrrolidin-2-one
T=25°C; Carboxylation; P=760 Torr; Electrolysis; Product distributionKinetics; Further Variations:Catalystssubstrate conc., catalyst conc., cathode material;
参考文献
Scialdone, Onofrio; Filardo, Giuseppe; Galia, Alessandro; Mantione, Davide; Silvestri, Giuseppe
Acta Chemica Scandinavica, 1999 , vol. 53, # 10 p. 800 - 806
反应条件
1: 54 percent / potassium hydroxide, 3-tert-butyl catechol, tetrabutylammonium bromide / 1 h / 120 °C
2: H2, <Rh(CO)2Cl>2, 1,2,5-triphenylphosphole, triethylamine / toluene / 6 h / 25 °C / 15001.2 Torr
View Scheme
参考文献
Neibecker, Denis; Reau, Regis; Lecolier, Serge
Journal of Organic Chemistry, 1989 , vol. 54, # 22 p. 5208 - 5210
反应条件
1: With thionyl chloride
12 h; Heating;
2: With ammonia in tetrahydrofuran; methanol
T=0 - 20°C; 1 h;
参考文献
Aramini, Andrea; Cesta, Maria C.; Coniglio, Silvia; Bijani, Christian; Colagioia, Sandro; D'Elia, Valerio; Allegretti, Marcello
Journal of Organic Chemistry, 2003 , vol. 68, # 20 p. 7911 - 7914
反应条件
hydrogenchloride; Zinc chloride
参考文献
BASF Corporation
Patent: US6555704 B1, 2003 ;
